Ai-driven multi-omics integration yields new aging clock gtAge
Peer-Reviewed Publication
Updates every hour. Last Updated: 26-Oct-2026 22:16 ET (27-Oct-2026 02:16 GMT/UTC)
Want to know your true biological age? A new study in Engineering introduces gtAge, an innovative aging clock built by combining IgG N-glycome and blood transcriptome data with a deep reinforcement learning tool called AlphaSnake. It predicts age more accurately than single-omics models and links biological aging to key health markers like cholesterol and blood sugar, offering a clearer view of how our bodies really age over time.
A recent study in Engineering reveals that IgG fucosylation is closely tied to severe COVID-19. Researchers found altered fucosylation—especially a drop in IgG2 fucosylation—in patients, linked to disease severity and body temperature. Key enzymes FUT8 and FUCA1 regulate these changes. The study also shows that Fuzheng Jiedu Decoction may ease inflammation by targeting fucosylation, offering new clues for treating severe COVID-19.
A review paper by scientists from Imperial College London examined how sensor‑integrated suits and soft exoskeletons could replace traditional exercise hardware with lightweight, modular, and intelligent systems that provide real‑time monitoring, dynamic loading, and personalized training—all while fitting inside a cramped spacecraft.
The new research paper, published on Apr. 17 in the journal Cyborg and Bionic Systems, discussed the challenges of the outer space environment and the musculoskeletal health complications derived from prolonged exposure. The currently employed solutions to address these complications are discussed, along with their limitations and potential solutions.
A research paper by scientists from Huazhong University of Science and Technology presented a jellyfish-inspired magnetic soft robot (J-MSR) capable of ultrafast swimming and seamless multimodal motion transitions in liquid environments.
The new research paper, published on Apr. 3 in the journal Cyborg and Bionic Systems, developed a jellyfish‑inspired magnetic soft robot (J‑MSR) that combining record‑breaking speed with seamless multimodal motion and functional integration.
Nanotechnology is emerging as a transformative force in cancer research, but the future of precision oncology will not be defined by drug delivery alone.
Influenza viruses, long known as harmful human pathogens, are now being reengineered into safe and powerful therapeutic tools. A new article in Engineering introduces a controllable PTC influenza platform using non-canonical amino acids to limit viral replication while boosting immune protection. This versatile system works as a next-generation vaccine against flu and other infections and shows strong potential as a cancer immunotherapy tool, opening new paths for future infectious disease and cancer treatments.
A new series of metal-organic frameworks (MOFs), donated as USC-CP-5-R, have been constructed using 14-connected metal-organic polyhedra as super-molecular building blocks (SBBs), exhibiting ultrahigh water stability. Functionalized with variable hydrophilic groups enables systematic tuning of the water adsorption performances, including uptake capacity and inflection point (a). These frameworks can efficiently capture atmospheric moisture, even in arid environments and can release collected water using low-grade solar thermal energy, highlighting their potential as a sustainable solution for freshwater production in water-scarce regions.
The team of Yanjun Jiang from Hebei University of Technology has constructed an efficient asymmetric reduction system for the synthesis of chiral alcohols by coupling electrochemical coenzyme regeneration with immobilized enzymes.
Scientists have developed smart polymeric nanoparticles that respond to unique signals within the tumor microenvironment to deliver immunotherapy precisely where needed.
Electrochemical nitrate reduction reaction (NO3RR) emerges as a sustainable approach for converting residual nitrate pollutants into valuable ammonia under ambient conditions, offering a promising alternative to the energy-intensive Haber-Bosch process. Compared to single-metal-site electrocatalysts, dual-metal-site (DMS) electrocatalysts show synergistic effects between adjacent metal sites, effectively regulating the electronic state and enhancing the catalytic activity and selectivity for NO3RR with multi-step proton and electron transfers. Further understanding on NO3RR is of practical significance for design of efficient DMS electrocatalysts.