CASHeart: A database of single cells chromatin accessibility for the human heart
Peer-Reviewed Publication
Updates every hour. Last Updated: 19-Nov-2025 17:11 ET (19-Nov-2025 22:11 GMT/UTC)
Recently, the research team led by Rui Jiang at Tsinghua University’s Department of Automation published a study titled “CASHeart: A database of single-cell chromatin accessibility for the human heart” in Quantitative Biology. This work systematically integrates and processes publicly available datasets to reveal cellular heterogeneity in the human heart, thereby advancing molecular insights into cardiac development, functional maintenance, disease pathogenesis, and therapeutic responses.
Recently, Xie Zhen's team from Tsinghua University published a research article titled "SPECIFIC: A systematic framework for engineering cell state-responsive synthetic promoters reveals key regulators of T cell exhaustion" in Quantitative Biology, proposing an integrated framework combining chromatin accessibility analysis and machine learning for rational design of synthetic promoters.
What has been the trajectory of water erosion model research in China? What are the most widely used models currently? What are the characteristics of research distribution across different regions? What shortcomings need urgent attention? Professor Qingfeng Zhang from Northwest A&F University, along with researchers from multiple institutions, systematically reviewed the research progress of water erosion models in China from 1982 to 2022 using a combination of bibliometric and statistical analysis methods, providing a panoramic perspective to answer these questions. Relevant study has been published in the journal Frontiers of Agricultural Science and Engineering (DOI: 10.15302/J-FASE-2024580).
Professor Xinzhang Song (Zhejiang A&F University) et al. conducted a study that revealed the response of soil CO2 emissions in bamboo forests of humid regions to straw mulching and its long-term effects. The research found that straw mulching not only significantly increased soil carbon emissions in the short term but also had enduring effects that persisted for at least three years after the removal of the mulching material. The study has been published in the journal Frontiers of Agricultural Science and Engineering (DOI: 10.15302/J-FASE-2025607).
Diswandi Nurba from IPB University in Indonesia at al. systematically evaluated the performance of four aeration system designs through a combination of Computational Fluid Dynamics (CFD) simulations and AHP-TOPSIS multi-criteria decision analysis, providing a scientific answer to this problem. The study had been published in Frontiers of Agricultural Science and Engineering (DOI: 10.15302/J-FASE-2024577).
An international team from countries including Iran, Iraq, Uzbekistan, and India has co-authored a review paper published in the journal Frontiers of Agricultural Science and Engineering (DOI: 10.15302/J-FASE-2024564). The corresponding author is Dr. Mohammad MEHDIZADEH from University of Mohaghegh Ardabili. The article outlines the potential applications of machine learning technology in weed management and provides insights for addressing the aforementioned issues. In simple terms, machine learning acts like an “intelligent brain” for farmland——it can analyze vast amounts of agricultural data, automatically identify patterns, and make precise decisions, shifting weed control from a “broad net” approach to “precision strikes”.
Recently, Dr. Muhammad Waqar Akram and his team from the Department of Farm Machinery and Power at University of Agriculture Faisalabad in Pakistan developed a “Machine Vision-Based Automatic Fruit Grading System”, offering a new solution. The related article has been published in Frontiers of Agricultural Science and Engineering (DOI: 10.15302/J-FASE-2023532).
Dr. Roaf Ahmad Parray from ICAR-indian agricultural research institute (ICAR-IARI) and his colleagues provide an answer in a study published in Frontiers of Agricultural Science and Engineering (DOI: 10.15302/J-FASE-2024572). In this research, an international team of scientists from India, Denmark, and the United States developed an innovative technology integrating spectral sensors, machine learning models, and an intelligent spraying system, successfully applying it to control black rot disease in cauliflower. This technology, comprising three core components—non-destructive detection, intelligent decision-making, and targeted pesticide application—significantly reduces pesticide use and offers new insights for green agriculture.
The latest annual meeting for the Global Education Deans Forum brought together 53 representatives from 40 institutions across 29 countries in Shanghai and Lijiang, China. An article published online in ECNU Review of Education on May 27, 2025, attempts to capture how a group of global education leaders view the promise and perils of AI amidst a rapidly changing educational landscape.