Novel mechanism reveals alveolar epithelial autophagy protects against Pseudomonas infection
Peer-Reviewed Publication
Updates every hour. Last Updated: 19-Nov-2025 15:11 ET (19-Nov-2025 20:11 GMT/UTC)
In a paper published in MedComm, a team of scientists identifies a critical role of the autophagy protein ATG5 in protecting lung epithelial cells from bacterial infections by regulating mitochondrial DNA release and controlling pyroptosis-induced inflammation via the non-canonical caspase-11 pathway.
The International Tubeless and Uniportal Society (ITUS) was officially launched! At ESTS 2025, 118 surgeons from 46 countries joined. The society focuses on six core goals—networking, education, training, research, mentorship, and advocacy—to promote the Tubeless concept worldwide. Tubeless isn’t just innovation—it’s a patient-centered philosophy of smaller incisions, faster recovery, and better care.
Using population sample survey data, this study shows bike-sharing boosts household consumption by up to 6.8% and dining by 4.9%, as a catalyst for local development. The positive externalities are driven by reduced commuting time, increased leisure, and lower rental costs.
“What Denisovans looked like, despite their genetic contributions to present-day East Asians and Oceanians?” This is one of the most important questions that has arisen since the discovery of the Denisovans 15 years ago. Now, recent research by a team led by FU Qiaomiei from the Institute of Vertebrate Paleontology and Paleoanthropology of the Chinese Academy of Sciences, and JI Qiang of Hebei GEO University has helped answer this question by confirming that a nearly complete hominin skull discovered near Harbin belongs to the Denisovan lineage. It dates back to at least 146,000 years ago.
A new editorial in Current Pharmaceutical Analysis underscores the critical role of method validation in biomarker analysis. Authors Dr. Behrouz Seyfinejad and Dr. Abolghasem Jouyban discuss challenges in bioanalysis, such as variability in biomarker data due to inadequate validation, and advocate for adherence to global guidelines to ensure accurate and reliable results in biomedical research.
Tsinghua University Press (TUP) and American Institute of Mathematical Sciences Press (AIMS) have forged a new collaboration to bring 12 of AIMS's esteemed STM journals to SciOpen.
A research team at Beihang University, led by Professor Jianghao Wu, has achieved a significant breakthrough in the design of propulsion systems for future low-altitude transport, particularly electric Vertical Take-Off and Landing (eVTOL) aircraft. Their pioneering work, recently published in the Chinese Journal of Aeronautics, introduces a novel analytical framework for ducted propellers, promising to make these advanced flying vehicles smaller, lighter, and more powerful. This research offers vital support for the burgeoning field of advanced air mobility, aiming to alleviate urban traffic congestion and utilize low-altitude airspace.
In the history of aircraft development, maneuverability has always been an important consideration in the design concept of aircraft. The requirements for aerodynamic characteristics are reflected in high lift-to-drag ratio, high lift coefficient, torque stability and so on. The occurrence of dynamic stall will lead to a sharp drop in lift and a rapid rise in drag, resulting in torque oscillation, which seriously restricts the improvement of aircraft performance, and even leads to aircraft crash in severe cases. The traditional passive flow control cannot cope with the real-time and changeable flow field environment, and the emergence of jet control provides a new way to solve the problem of dynamic stall. Although the research of single jet technology has been relatively sufficient, there are few comparative studies on steady jet and synthetic jet, and there is also a lack of related research on dual synthetic jets. Therefore, it is imperative to fill this research gap.
Operating drones across air and water boundaries poses serious aerodynamic risks due to complex gas-liquid flow interactions. A new finite vortex rotor model developed by researchers in China provides unprecedented insight into how rotors behave near free water surface. The study introduces a predictive boundary that separates safe and unsafe flight zones, offering a powerful tool for the design and control of aerial-aquatic rotorcraft.