A new study published in Engineering offers fresh insights into Alzheimer’s disease, revealing that inhibiting an enzyme called ST6Gal-I can reduce levels of BACE1 and amyloid-β plaques, which are key factors in the disease’s progression. This research underscores the potential of targeting glycosylation pathways as a strategy for developing new treatments for Alzheimer’s.

In a recent article published in Engineering, researchers Li Guo and Jinghai Li from the Chinese Academy of Sciences explore the future development of artificial intelligence (AI), emphasizing the need for consistency in the logical structures of datasets, AI models, model-building software, and hardware. They argue that while current AI systems excel at handling statistical properties of complex systems, they face challenges in effectively representing spatiotemporal complexity patterns. The authors propose integrating principles of multilevel complexity into AI development to enhance its functionality and reliability in engineering applications.

Perovskite-structured BaFe_0.4Co_0.4Zr_0.1Y_0.1O_3-δ (BFCZY) exhibits proton-electron-oxygen ion triple conductions and high catalytic activity of oxygen reduction (ORR) and oxygen evolution reaction (OER) at low temperatures. Although it has stability problems in a humid air environment, the degradation mechanism of BFCZY and the influences of temperature, steam content and polarization on its stability have been rarely studied. The activity and stability of the BFCZY oxygen electrode are significantly improved through heterointerface engineering by infiltrating the BaCoO₃ (BCO) catalyst. It is imperative to fill this research gap, as it is crucial for promoting the commercial development of reversible protonic ceramic electrochemical cells (R-PCECs).

Highly efficient chemiresistive gas sensors are crucial for numerous applications. Notably, though the generally high working temperature brings fine sensing performance, as well as causing high power consumption, poor safety, and disabled operational stability. Thanks to the cost-effective, simplified structure and integrated diversity, room temperature (RT) operational mode has been put forward and applied in gas sensor devices. However, insufficient limits of detection limit (LOD) and disappointingly long detection time limit their broad applications, meanwhile, the existing sensing mechanism based on the charge transfer between the analyte gas and the oxide surface hampers room temperature gas sensing with low LOD and rapid speed.

On June 18, 2025, Clarivate released the 2025 Journal Citation Reports™ (JCR™). Eighteen English-language STM journals published by Tsinghua University Press received a Journal Impact Factor (JIF), with 13 (72.2%) journals ranking in the Q1 quartile.