Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal cord compression. This condition is more prevalent in Asian countries and has been associated with various genetic and hormonal factors. Recent insights reveal the potential role of interferon (IFN) signaling in the pathogenesis of OPLL, particularly the type I IFN pathway, which is known to play a role in innate immune responses and bone formation. A single-cell transcriptome profiling study has identified the activation of type I IFN signaling in ossified posterior longitudinal ligament, suggesting a therapeutic target for OPLL.

The International Journal of Extreme Manufacturing has published a study by Professor Zhenyu Zhang and his team at Dalian University of Technology, detailing their innovation of an eco-friendly photocatalytic chemical mechanical polishing (PCMP) slurry specifically designed for diamond polishing. This innovative, green PCMP slurry not only delivers high-quality and efficient polishing outcomes but also adheres to sustainable practices, marking a substantial leap forward in material processing technology. Their research offers fresh perspectives on achieving an atomic-level diamond surface, paving the way for potential applications in high-performance devices.