Identification of regulatory GPCRs by single-cell trajectory inference
Peer-Reviewed Publication
Updates every hour. Last Updated: 18-Jul-2025 17:11 ET (18-Jul-2025 21:11 GMT/UTC)
A recently published paper in Science China Life Sciences reports an interdisciplinary study utilizing single-cell sequencing data analysis to identify GPCRs involved in the regulation of adipogenesis. Through both in vitro and in vivo validation, the authors find that ADGRD1 promotes adipogenesis, whereas GPR39 inhibits this process.
Recently, Yulong Yin/Fengna Li from the Institute of Subtropical Agriculture Chinese Academy of Sciences published a paper entitled "Metabolome and RNA-seq reveal discrepant metabolism and Metabolism" in SCIENCE CHINA Life Sciences. This study investigated the metabolic difference of longissimus dorsi muscle between Taoyuan black pigs (Chinese native breed, obese) and Duroc pigs (lean) at different ages, and revealed the mechanism of muscle-adipose tissue interaction mediated by muscle-derived secretory metabolites.
A new study published in National Science Review examines China's trends in primary particulate matter (PM) emissions from 1960 to 2019, revealing significant transformations in PM size fractions and carbonaceous compositions. Despite an overall decline in emissions, finer particles like PM2.5 and carbonaceous fractions (e.g., black carbon and organic carbon) have increased. These findings underscore the critical role of technological advancements and policy-driven measures in shaping the trajectory of air quality improvements.