Cancer and cardiovascular diseases (CVDs) share common risk factors, and treatments for cancer have the potential to increase the risk of CVDs. Researchers have elaborated on the importance of recognizing the indicators, patterns, predictive outcomes, and challenges associated with CVD risks in cancer patients and survivors. Proactive management and early detection are essential to improving the overall health outcomes and quality of life for patients with cancer.

This work reports the design of an efficient multiband UC system based on Ln³⁺/Yb³⁺-doped core-shell upconversion nanoparticles (Ln/Yb-UCNPs, Ln³⁺=Ho³⁺, Er³⁺, Tm³⁺). In the design, Ln³⁺ ions are incorporated into distinct layers of Ln/Yb-UCNPs to function as near-infrared (NIR) absorbers across different spectral ranges. This design achieves broad multiband absorption withtin the 1100 to 2200 nm range, with an aggregated bandwidth of approximately 500 nm. It can effectively extend the photovoltaic performance of silicon solar cells.

High-Resolution Anisotropic Tomography Reveals Mantle Flow Complexity and Slab-Plume Interactions, Redefining Subduction Zone Dynamics

This study presents an enhanced nuclease prime editor (uPEn) that significantly improves gene knock-in and knockout efficiency in mammalian zygotes. The researchers optimized prime editing by incorporating a ubiquitin variant regulator of double-strand break (DSB) repair, enhancing editing precision while maintaining high efficiency. The study validates the system by editing PPARG, a key regulator of fat metabolism, in Hu sheep and mice. Additionally, a multiplexed approach was applied to simultaneously knock out MSTN and knock in PPARG in sheep embryos, demonstrating uPEn's potential for agricultural and biomedical applications.

A recent review has introduced the concept of scaling laws to urban ecosystems, offering a novel perspective on city growth and ecological balance. By merging thermodynamic principles with urban metabolism, researchers have created a framework that not only predicts shifts in urban ecosystems but also provides insights for more sustainable urban planning. This approach illuminates the delicate balance between urban expansion and ecological sustainability, promising to reshape how we manage cities in an era of rapid growth and environmental change.