Sulfur amino acid restriction enhances fat loss and metabolic health
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Updates every hour. Last Updated: 12-Jul-2025 04:11 ET (12-Jul-2025 08:11 GMT/UTC)
A new study reveals that Epstein-Barr virus (EBV) infection exacerbates ulcerative colitis (UC) by driving macrophage pyroptosis through the upregulation of glycolysis. This finding provides a potential therapeutic target for mitigating EBV-induced intestinal inflammation. The study, titled "Epstein-Barr virus infection exacerbates ulcerative colitis by driving macrophage pyroptosis via the upregulation of glycolysis," was published on January 21, 2025, in Precision Clinical Medicine.
A recent review in Engineering presents new methods for enhancing chiral optical signals. Chirality is important in many fields, but its optical signals are weak and hard to measure. The research covers strategies like tailoring optical fields, using photonic resonance, orbital angular momentum (OAM) beams, metasurfaces with bound states in the continuum (BICs), and nonlinear optics. These methods offer new ways to study chiral optics, though challenges remain.
A team from China Agricultural University has developed a novel synergetic cooling and charging strategy for high-power direct current fast charging in electric vehicles. Published in Engineering, the approach uses a gallium-based liquid metal flexible charging connector (LMFCC). This new solution aims to overcome the challenges of thermal shocks and inefficient cooling during high-current charging, with promising results in improving charging system performance.
A review in Engineering explores organ preservation, which is a critical area due to the global organ shortage. Current methods like static cold storage and machine perfusion have limitations. Cryopreservation shows promise, but challenges remain. The research details the history, techniques, and prospects for different organs, aiming to improve preservation and address the shortage.
The effect of high magnetic field on the directional solidification structure of Al-18 at.%Ni peritectic alloy was studied. In the absence of magnetic field, the alloy forms a dendritic structure with preferred orientation, and a transverse plate-like structure with block eutectic is formed under a 6 T magnetic field. At 0 T and 5 μm/s, the Al3Ni phase was preferentially oriented along the <010> direction, while the sample prepared at 100 μm/s exhibited no preferred orientation. Under 6 T magnetic field, 5 μm/s pulling makes the solidification mode change from peritectic reaction to hypereutectic reaction, and the Al3Ni phase presents orientation. When the pumping speed increases to 20-100 μm/s, the peritectic reaction is still dominant. The primary Al3Ni2 phase is oriented along the direction, and the peritectic phase is attached to it to form a preferred orientation. The magnetic field regulates crystal orientation and solute transport through the coupling of magnetic torque, thermo-electro-magnetic force and magnetic field force, and its influence mechanism shows a significant dependence on pulling speed.
This study, published in Earth and Planetary Physics, explores the subduction thermal state, slab metamorphism, and seismic activity in the Makran Subduction Zone. Using 3-D thermal modeling, the research examines the thermal structure of the subducting slab, the resulting metamorphic processes, and their relationship to earthquake generation. The findings provide crucial insights into the dynamics of subduction zones, with significant implications for understanding seismic hazards in the region.
A study elucidating the seismogenic structures of the Ms 6.2 Jishishan earthquake that struck China on December 18, 2023, has recently been published in Earth and Planetary Physics. The research employed relocation, focal mechanism solutions, and rupture process inversion to characterize the causative faults and rupture dynamics of this seismic event.