Professor Ke Zheng of East China Normal University launches the "Education Powerhouse Research Series," addressing China's transition from a "large" to a "strong" education system. Grounded in real-world challenges, the series seeks to bridge the gap between theory and practice while contributing Chinese perspectives to global education governance.

Erectile dysfunction is one of the most frequent and distressing complications after radical prostatectomy, significantly impairing patients’ quality of life. A new review published in UroPrecision summarizes current evidence on penile rehabilitation strategies, including oral medications, intracavernosal injections, and vacuum devices, and proposes a risk-stratified algorithm to guide clinical decision-making. 

This review is part of the themed issue “Distinct Themes for the Advanced Practice Providers in Andrology”

Robot-assisted radical prostatectomy (RARP) has become the standard treatment for localized prostate cancer. However, postoperative urinary incontinence and erectile dysfunction remain common complications. A new review published in UroPrecision systematically examines nerve-sparing techniques during RARP, including anatomical foundations, surgical planes, innovative approaches, and patient selection tools, providing a practical guide for balancing cancer control and functional preservation.

The advent of the evolutionary scale modeling (ESM) series of protein language models (PLMs) is a significant innovation in the convergence of large language models (LLMs) with protein representation. These models, trained on large amounts of unlabeled protein sequence data, learn the intricate patterns of mutation and conservation that have sculpted protein families through evolutionary history. ESM has become a widely used foundation model family for protein representation and downstream biological tasks.

Oral nanomaterial formulations enhance drug stability, solubility, mucosal penetration and targeted delivery for gastrointestinal therapy. This review compares metallic and non-metallic nanomaterials and highlights the strong clinical translation potential of non-metallic systems, especially selenium nanoparticles (SeNPs).

Over the past decades, combination therapy has become a promising strategy to combat antimicrobial resistance. Compared with monotherapy, drug combinations can enhance efficacy and delay resistance. However, experimental identification of drug–drug interactions (DDIs) remains time-consuming and limits large-scale screening.

Much attention has been paid to the transdermal delivery of medicinal agents owing to its advantages in the administration. The first pass effect in the liver can be avoided and the bioavailability is enhanced by the drug delivery through the skin. The patients’ compliance is good because almost no pains are involved in applying transdermal dosage forms (e.g., ointments and patches). The long-lasting efficacy of medicines is obtainable as long as the dosage forms adhere to the skin. The administration is easily stopped by removing the dosage forms when necessary.

In short, we report an inverse phase enhancement (IPE) strategy to fabricate high-performance graphene paper (IPE-GP) exhibiting high strength (63.3 MPa) and high thermal conductivity (1325 W/m·K) at a minimal polymer loading of 5.9%. Using this conspicuous IPE-GP, we fabricated graphene composites that attained a record in-plane thermal conductivity of 802 W/m·K of polymer bulk composites.