A team of researchers led by SU Bing from the Kunming Institute of Zoology of the Chinese Academy of Sciences, along with collaborators from BGI-Research and Liaoning Normal University, built the first three-dimensional, single-cell atlas of an entire lamprey brain, which is essentially a high-resolution map showing the location of every cell and which genes are active in each cell.

With the increasing clinical use of anti-amyloid-β monoclonal antibodies in Alzheimer’s disease in China, some patients have completed or are approaching the predefined treatment period, leading to emerging clinical questions regarding post-treatment maintenance, discontinuation, monitoring, and retreatment. However, no consensus has yet been established on long-term management or sequential-like treatment strategies after anti-amyloid-β monoclonal antibody therapy. Based on current clinical evidence and the practical experience of Renji Cognitive Center, this article proposes an experience-based protocol for sequential-like management of anti-amyloid-β monoclonal antibody therapy. The protocol uses amyloid PET-derived Centiloid values as the core objective reference and recommends stratified management according to clinical clearance status and prior amyloid clearance rate. This protocol is intended to provide a clinical reference and requires further validation and optimization through real-world studies and long-term follow-up.

A research team from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences, in collaboration with a team from Xiamen University spatially resolves the atomic -scale interplay between hole transfer dynamics and the evolution of water oxidation intermediates on faceted BiVO₄ particles.

Mechanoluminescence(ML) directly converts mechanical energy into light, offering a promising route for energy-free sensing. Here, we report a low cost, stable Al₂O₃:Cr³⁺ platform with self-recoverable near-infrared emission. A reversible stress induced ionization–recapture mechanism, together with defect engineering, annealing, and heterostructure optimization, delivers strong and recoverable luminescence. The material enables flexible ML paper and alloy-surface coatings for real time structural stress visualization.

Quantum cascade laser (QCL) frequency combs face bandwidth limitations (~100 cm⁻¹) that challenge carrier-envelope offset frequency locking. This work demonstrates ultra-broadband QCLs using a diagonal multi-state-to-continuum active region design, achieving ~600 cm⁻¹ electroluminescence at 298 K. Devices deliver 2.72 W peak power with 1.2 μm lasing bandwidth and 1.93 μm at 80 K, advancing single-stack mid-infrared semiconductor lasers for spectroscopy and communications.

A new genome and multiomics study has revealed how Clinacanthus nutans, a traditional medicinal plant widely used in Southeast Asia, produces different bioactive compounds in different organs. 

Researchers have developed a water-responsive polyvinyl alcohol-based film reinforced with a chitosan-pectin hybrid polysaccharide that maintains mechanical stability under high humidity and transforms into a high-performance adhesive upon water activation and hot-pressing, offering a sustainable alternative to petroleum-based films and formaldehyde-containing adhesives.

Fibrotic scarring is one of the major reasons why the injured spinal cord struggles to repair itself. 

Antibody-drug conjugates (ADCs) are among the most promising advances in modern oncology—precision-guided missiles that deliver potent cytotoxic agentsdirectly to cancer cells while sparing healthy tissue.