Researchers from the Harbin Institute of Technology (HIT) have proposed a 7-axis synchronization strategy for simultaneously realizing high accuracy, high efficiency and large scale in multi-axis linkage laser texturing of freeform surface, based on the unified control of a 5-axis linkage motion platform with a 2-dimensional galvanometer. And corresponding specialized machine tool implemented with the proposed strategy has been developed, which shows significantly promoted performance of laser texturing on freeform surface than the traditional 5-axis linkage strategy.

Ovarian cancer, a deadly gynecologic malignancy, has seen a significant shift in its treatment paradigm with the introduction of poly (ADP-ribose) polymerase (PARP) inhibitors, which are now standard in the maintenance setting following first-line chemotherapy. This retrospective cohort study investigates the real-world effectiveness and safety of olaparib, a PARP inhibitor, in patients with newly diagnosed advanced-stage, high-grade serous ovarian cancer who are HRD positive but BRCA wild-type, a demographic less extensively explored in previous research. The primary goal was to assess the 1-year progression-free survival (PFS) rate of olaparib maintenance therapy in this specific patient group, offering insights into its potential as a therapeutic option.

In the research, they investigate the reason for the long DNN model warm-up time in Web apps and find that compiling WebGL programs into binaries takes most of the time. Inspired by this finding, they propose WPIA, an approach that reduces the DNN warm-up time in Web apps by precompiling WebGL programs offline.