Breakthroughs in tuberculosis vaccine and drug development pave way for global health advancements
Peer-Reviewed Publication
Updates every hour. Last Updated: 7-Jul-2025 11:11 ET (7-Jul-2025 15:11 GMT/UTC)
A landmark review in Molecular Biomedicine outlines cutting-edge strategies to combat tuberculosis (TB), highlighting novel vaccines, AI-driven antigen discovery, and next-gen therapies to address drug-resistant strains and improve global TB control.
Addressing the longstanding challenges of multi-mode fiber (MMF) transmission, the research team led by Prof. Qiming Zhang and Associate Prof. Haoyi Yu from the School of Artificial Intelligence Science and Technology (SAIST) at the University of Shanghai for Science and Technology (USST) has introduced a groundbreaking solution. The team successfully integrated miniaturized multilayer optical diffractive neural networks (DN2s) onto the distal end of MMFs, enabling full-optical image transmission. Regarded as an ONN, the free-space diffractive neural networks (DN2s), have been proposed as more efficient ANN approaches based on deep learning to directly process the optical matrix multiplication at the speed of light, and realizing the high number of connectivity in ANNs, such as optical image classification, decryption and phase detection.
In an article featured in Science China Earth Sciences, researchers from Tianjin University elucidate the coupling relationship between soil fungi and reactive minerals in ecosystems by utilizing global fungal carbon stocks, mineral-associated carbon stocks, and high-resolution nanoscale secondary ion mass spectrometry. They also reveal the mechanisms of fungal-nanoparticle interactions belowground. These findings provide new insights into the critical role of microorganisms in soil carbon stability and storage.
In June 2024, southern China experienced record-breaking heavy rainfall, resulting in devastating societal and economic impacts. The underlying cause of this extreme event remained unclear until this study, published in Science Bulletin, provided new insights. Based on analyses from numerical simulations using an Earth System Model (ESM), an international team of scientists identified excessive spring land heating over the Tibetan Plateau as the primary factor driving the catastrophic June 2024 rainfall in southern China.
A research team from the Eye & ENT Hospital of Fudan University, China, has developed a novel biocompatible nanoadhesive for corneal transplantation. The nanoadhesive is based on tetrahedral framework nucleic acids combined with functionalized polycationic recombinant proteins. This unique composition minimizes the risks of tissue necrosis and inflammation associated with polymeric adhesives while inhibiting bacterial growth and promoting tissue repair. This work demonstrates an efficient strategy to break through the bottleneck of current ophthalmic adhesives.