Stereoisomeric engineering for critical balance of solvation and adsorption capability
Peer-Reviewed Publication
Updates every hour. Last Updated: 14-Jul-2025 09:11 ET (14-Jul-2025 13:11 GMT/UTC)
This cross-sectional study, spanning from December 2020 to December 2021, delves into the prevalence and risk factors of carotid artery stenosis and plaque across China. Involving 194,878 adults aged 40 and above from 31 provinces, the research leverages data from the China Stroke High-risk Population Screening and Intervention Program (CSHPSIP), adhering to the STROBE reporting guideline. The study's objective is to address the knowledge gap regarding these conditions' prevalence and associated risk factors, which previous studies have inconsistently reported.
Computer scientists developed E2URec, an efficient unlearning method for LLM-based recommenders. It uses a lightweight module and dual teachers to forget specific data while maintaining performance, which innovates privacy handling in recommendation systems.
Researchers from California State University Northridge (CSUN), National University of Singapore (NUS), NASA Jet Propulsion Laboratory (JPL), and University of Wisconsin-Madison (UW-Madison) have introduced a new concept called autonomous additive manufacturing (AAM), where AI agents take over tasks traditionally managed by human operators. This breakthrough represents a major step toward creating autonomous manufacturing systems, offering improvements in knowledge representation and multi-modal capabilities in additive manufacturing (AM) processes.
The lead Ph.D. candidate, Mr. Haolin Fan, explained: "In the era of generative AI, this research points out a future where human expertise and AI collaborate seamlessly, leading to more resilient and adaptable manufacturing systems that could transform industrial production."
Research team proposed RSLR, a robust self-training approach with label refinement for unsupervised domain adaptation under label noise. It uses LNet for pseudo-labeling and TNet for target-specific training, achieving successful performance on benchmark datasets.
Research team designed PBCounter, a weighted model counting solver for pseudo-Boolean formulas. It uses variable elimination and dynamic programming with ADDs, outperforming state-of-the-art CNF-based solvers in experiments.
The anti-melanogenesis effect of ligustroside derived from Ligustrum japonicum and its underlying mechanisms are explored.
The protective effects of Lepidium draba L. on cyclophosphamide-induced hepatotoxicity and nephrotoxicity are explored in rats.
In this March 2025, The Lancet Respiratory Medicine (JCR Q1, IF: 38.7), the leading journal in the fields of respiratory and critical care medicine, published a phase 2 clinical study article on China's first DPP-1 inhibitor, HSK31858, led by Academician Nan-shan Zhong and Professor Wei-jie Guan from the First Affiliated Hospital of Guangzhou Medical University and Guangzhou National Laboratory. The article entitled "Effects of the DPP-1 Inhibitor HSK31858 in Adults with Bronchiectasis in China (SAVE-BE): A Phase 2, Multicentre, Double-Blind, Randomised, Placebo-Controlled Trial.", by focusing on non-cystic fibrosis bronchiectasis patients, marks a significant breakthrough in China's bronchiectasis treatment.
The article presents the efficacy and safety data of the DPP-1 inhibitor in Chinese bronchiectasis patients, offering a new therapeutic strategy. Results show that compared with traditional treatments, HSK31858 significantly improves patient symptoms and reduces acute exacerbation frequency. This finding holds promise for bronchiectasis patients and will further advance the field of respiratory medicine.
Recently, the research team led by Professor Heping Zhang at the Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Inner Mongolia Agricultural University, published a groundbreaking study in the prestigious journal Science Bulletin. Titled "A Genomic Compendium of Cultivated Food-Derived Lactic Acid Bacteria Unveils Their Contributions to Human Health", the study details the development of the comprehensive genomic dataset of food-derived lactic acid bacteria (FLAB). By systematically revealing their diversity and potential applications in food fermentation and human health, this research provides valuable scientific insights and foundational support for future studies and practical applications of LAB.