Novel gene therapy platform restores muscle function in models of Duchenne muscular dystrophy
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Jun-2026 05:15 ET (22-Jun-2026 09:15 GMT/UTC)
A new treatment platform developed by researchers at The University of Texas MD Anderson Cancer Center was able to deliver messenger RNA (mRNA) of the full-length DMD gene into preclinical models of Duchenne muscular dystrophy, successfully restoring the production of an important muscle protein, dystrophin, and dramatically improving muscle strength, endurance and function in vivo.
A research team in Japan has developed an efficient and minimally invasive cancer detection device that uses high-performance zinc oxide nanowires to selectively capture extracellular vesicles (EVs) from bodily fluids. Using this device, researchers successfully captured cancer-related EVs from the blood serum of ovarian cancer patients.
An unexpected lab observation led a team of scientists to discover how diet can influence survival in animal models of glioma, one of the most aggressive and deadly forms of brain cancer. Researchers reveal how limiting a single nutrient, the amino acid methionine, in the diet destabilized DNA organization and led to cancer cell death and increased animal survival. These findings open new possibilities for treating one of the most challenging forms of brain cancer.
A new study by investigators from Mass General Brigham Cancer Institute found that an ultrasensitive blood test called HPV-DeepSeek could help identify which people with HPV-associated head and neck cancer still had cancer cells in their bodies after surgery and may benefit the most from additional treatments. Their results are published in Science Translational Medicine.
Three cancer researchers are being honored by the ECOG-ACRIN Cancer Research Group for their outstanding contributions. Dr. Valsamo Anagnostou from Johns Hopkins University is the Young Investigator of the Year for her pioneering work in lung cancer. Dr. Jordan Berlin of Vanderbilt University receives the Remarkable Mentor in Oncology Award for his dedication to nurturing oncology talent. Dr. Olisaemeka Ogbue of Mayo Clinic is awarded a grant for his innovative research on cancer survivorship.
Daniel Daneshvar, MD, PhD, director of the HealthSpan Lab and Chief of the Department of Physical Medicine and Rehabilitation at Mass General Brigham, and Charlotte Luster, of the HealthSpan Lab, are the senior and lead authors of a paper published in Neuroepidemiology, “Brain Cancer Mortality following Traumatic Brain Injury (TBI): A TBI Model Systems Study.”
Many of the deadliest forms of cancer are caused by a pathological mutation in the RAS protein. Yet, to date, no effective treatment for this cancer protein has been found. A new research approach aims to prevent the protein from forming in the first place by destroying its blueprint – the mRNA. Based on this strategy, the research group led by Peng Wu at the Max Planck Institute of Molecular Physiology has now developed a new type of “molecular eraser” targeting the mRNA of the cancer protein NRAS.