Generative AI is more efficient than nature at designing proteins to edit the genome
Peer-Reviewed Publication
Updates every hour. Last Updated: 11-Oct-2025 15:11 ET (11-Oct-2025 19:11 GMT/UTC)
Researchers at Integra Therapeutics, in collaboration with the Pompeu Fabra University (UPF) Department of Medicine and Life Sciences (MELIS) and the Center for Genomic Regulation (CRG), have designed and experimentally validated new synthetic proteins that can edit the human genome more efficiently than proteins provided by nature. This work, a global pioneer published today in the journal Nature Biotechnology, will be of great use in improving the current gene editing tools used in biotechnology research and personalized medicine by developing cellular (CAR-T) and gene therapies, especially to treat cancer and rare diseases.
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