Mapping RNA-protein 'chats' could uncover new treatments for cancer and brain disease
Peer-Reviewed Publication
Updates every hour. Last Updated: 11-Oct-2025 11:11 ET (11-Oct-2025 15:11 GMT/UTC)
Researchers at London Health Sciences Centre Research Institute (LHSCRI) have launched a Phase II clinical trial that aims to treat renal cell carcinoma (kidney cancer) by inserting microscopic beads filled with radiation directly into blood vessels surrounding cancerous tumours. The goal is to improve patient outcomes through a new treatment option.
Three graduate students in CSHL’s dos Santos lab have developed a tool called MaGNet to quickly measure changes in mouse mammary glands. This open-source technology can be used to study how hormonal changes affect mammary glands and may one day allow for earlier breast cancer diagnoses.
• Most patients receiving chemotherapy with taxanes or platinum salts develop painful neuropathy in hands and feet, often forcing dose reduction or treatment interruption.
• Published in Clinical and Translational Oncology, the study demonstrates that topical application of Oncapsisens® delays and reduces neuropathic symptoms, paving the way for new preventive options for cancer patients.
Topics range from security in times of crisis to personalised treatment for colorectal cancer / A total of approximately €20.5 million for the first funding period
In response to cellular stress, the protein CxUb is activated to identify damaged proteins, thereby maintaining cellular health. The discovery could lead to ways to improve the treatment of cancer and neurodegenerative diseases / publication in ‘Molecular Cell’