New PET tracer identifies diverse invasive mold infections behind life-threatening illnesses in cancer and transplant patients
Peer-Reviewed Publication
Updates every hour. Last Updated: 28-Jun-2025 20:10 ET (29-Jun-2025 00:10 GMT/UTC)
Devanand Sarkar and a team of scientists at VCU Massey Comprehensive Cancer Center found that TAF2 is overexpressed in hepatocellular carcinoma patients compared to individuals with healthy livers. Through preclinical research, they discovered that TAF2 regulates the survival of hepatocytes—the functional cells of the liver—and tumor formation. Their study—recently published in the journal Hepatology—also demonstrates that TAF2 cooperates with the MYC gene, another known major driver of cancer, to accelerate tumor growth.
The University of Cincinnati Cancer Center (UC), The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) and Jabez Biosciences are partnering to open a new phase 1 clinical trial studying JBZ-001, a potential new treatment for acute myeloid leukemia (AML).