A new gene signature and patient-derived models reveal the malignant neuroblastoma cells that have long been missed.

National Comprehensive Cancer Network participates in annual conferences for the International Gynecologic Cancer Society and Philippine Society of Medical Oncology in efforts to standardize cancer treatment recommendations.

An ultrasound-responsive micronanorobot combines a collagenase-secreting bacterium, bismuth ferrite nanoparticles, the drug DM4 and a targeting ligand to treat nonmuscle-invasive bladder cancer. After intravesical delivery, it degrades tumor matrix, enhances drug penetration, and ultrasound triggers reactive oxygen species, achieving 90.8% cell death in vitro and 82.4% tumor inhibition in mice. The system also promotes antitumor immunity, increasing CD8+ T-cell infiltration and shifting macrophages toward the M1 phenotype.

According to international studies, taking Acetylsalicylic acid daily can protect people with Lynch syndrome from developing colorectal cancer – even at low doses. Researchers from the University Hospital Bonn (UKB), the University of Bonn, and the Center for Integrated Oncology (CIO) Bonn, in collaboration with the self-help organization SemiColon, have now found that these scientific findings have so far been insufficiently incorporated into clinical practice. The results of the LYNX study have now been published as a letter in the journal *The Lancet Gastroenterology & Hepatology*.