News Release

48th Annual UNC Lineberger Scientific Symposium — Cancer Discovery and Application: The Road to Improved Patient Outcomes

Sept. 9–10, 2025 | Friday Center, Chapel Hill, NC | Livestream Available | Free Registration (Required)

Meeting Announcement

University of North Carolina Health Care

48th Annual UNC Lineberger Scientific Symposium — Cancer Discovery and Application: The Road to Improved Patient Outcomes

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The 48th Annual UNC Lineberger Scientific Symposium is a day-and-a-half meeting exploring advances across the cancer research continuum—from molecular discovery to clinical application to population impact—that are improving cancer outcomes. The meeting features 16 talks by leaders in cancer research that bridge basic, translational and population sciences.

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Credit: UNC Lineberger Comprehensive Cancer Center

Join leading cancer researchers, clinicians, and population scientists for the 48th Annual UNC Lineberger Scientific Symposium, a day-and-a-half meeting in Chapel Hill, North Carolina, exploring advances across the cancer research continuum—from molecular discovery to clinical application to population impact—that are improving cancer outcomes.

This year’s symposium commemorates the 50th anniversary of UNC Lineberger’s designation as a National Cancer Institute-designated cancer center.

It will feature 16 talks by leaders in cancer research that bridge basic, translational and population sciences.

The meeting will be livestreamed and is free, though registration is required.

Featured Speakers and Topics

Lewis Cantley, PhD – Dana-Farber Cancer Institute
Protein kinase specificity and cellular regulation in cancer

Melissa B. Davis, PhD – Morehouse School of Medicine
Genomic inequities and population-level cancer disparities

Julian Downward, PhD – Francis Crick Institute
RAS oncogenic signaling and immune evasion strategies

Tony Hunter, PhD – Salk Institute
Four decades of tyrosine phosphorylation and its therapeutic impact

William G. Kaelin Jr., MD – Dana-Farber Cancer Institute
The VHL tumor suppressor and targeting the “undruggable”

Edison T. Liu, MD – The Jackson Laboratory
Genomic biology of triple-negative breast cancer

Elaine Mardis, PhD – The Ohio State University
Genomic diversity and treatment outcomes in Black AML patients

W. Kimryn Rathmell, MD, PhD – The Ohio State University
Lineberger’s past and future: a model for comprehensive cancer care

Kurt M. Ribisl, PhD – UNC Gillings School of Global Public Health
Cancer prevention through interdisciplinary public health strategies

Arlene Sharpe, MD, PhD – Harvard Medical School
CRISPR-powered discovery of immunotherapy targets

Kevan Shokat, PhD – UC San Francisco
Breaking the barrier: drugging K-Ras

Melissa Troester, PhD – UNC Gillings School of Global Public Health
Multimodal data to optimize breast cancer outcomes

Stephanie B. Wheeler, PhD, MPH – UNC Gillings School of Global Public Health
Collaborative frameworks for improving cancer care in NC

Kwok-Kin Wong, MD, PhD – NYU Langone Health
Targeting lung squamous cell carcinoma

Yue Xiong, PhD – Cullgen Inc.
Targeted protein degradation as a therapeutic platform


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