Fig. 1. Fabrication and characterization of Aln-Lipo-DQ. (IMAGE)
Caption
(A) Schematic depiction of liposomes modified with alendronate encapsulates senolytic drugs for the targeted delivery to osseous tissue to eliminate senescent cells. (B) The size and distribution of Aln-Lipo-DQ were analyzed by DLS. (C) TEM visualizes the structure of Aln-Lipo-DQ. (D) Stability of Aln-Lipo-DQ at room temperature for 48 h. (E) The zeta potential of Aln-Lipo-DQ and Lipo-DQ. (F) In vitro dasatinib and quercetin release in PBS (pH 7.4) containing 1% Tween 80 at 37 oC within 48 h.
Credit
Rong Li, Yaohua Wei, Changhao Xiong, et al.
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