EurekAlert! Cancer Research

News Releases

Updates every hour. Last Updated: 4-May-2025 01:09 ET (4-May-2025 05:09 GMT/UTC)

19-Mar-2025

Owen Witte awarded international Harrington Prize for Innovation in Medicine

University of California - Los Angeles Health Sciences
Grant and Award Announcement

The Harrington Discovery Institute at University Hospitals and the American Society for Clinical Investigation have awarded Dr. Owen Witte(Link is external) (Link opens in new window) with the twelfth annual Harrington Prize for Innovation in Medicine.

19-Mar-2025

Classifying childhood brain cancers by immune response may improve diagnostics and treatments

University of Pittsburgh
Peer-Reviewed Publication

The new approach establishes an opportunity to harness the success of immunotherapies that revolutionized the treatment of childhood leukemias for childhood brain cancers.

Journal: Science Translational Medicine
Funder: NIH/National Institutes of Health, Botha-Chan Research Fund, Brain Tumor Funders' Collaborative, Ellie Kavalieros DIPG Research Fund, Office of the Assistant Secretary of Defense for Health Affairs, UPMC Children’s Hospital Foundation, Haley Weiss Memorial Fund, Children’s Brain Tumor Network, Gift From a Child, Swifty Foundation

19-Mar-2025

Removing a protein ‘signal jammer’ improves immunotherapy

St. Jude Children's Research Hospital
Peer-Reviewed Publication

St. Jude researchers identified a protein, voltage-dependent anion channel 2 (VDAC2), that tumors use as a “signal jammer” to prevent cancer cell death and evade the immune system’s functioning.

Journal: Nature
Funder: NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health

19-Mar-2025

Mayo Clinic researchers identify a measurable genetic mutation as a significant predictor of metastasis and survival in pancreatic cancer

Mayo Clinic
Peer-Reviewed Publication

A new study by Mayo Clinic Comprehensive Cancer Center researchers found that the presence of a specific genetic mutation — KRAS circulating tumor DNA (ctDNA) — strongly indicates a higher risk of cancer spread and worse survival rates for patients with pancreatic ductal adenocarcinoma (PDAC). The mutation was identified using a readily available and clinically approved blood and abdominal fluid test.

Journal: Annals of Surgical Oncology

19-Mar-2025

$1.2M grant will fund study on neighborhood environment’s possible role in cancer risk

University of Arizona Health Sciences
Grant and Award Announcement

A grant from the American Cancer Society will allow researchers to develop a comprehensive picture of the factors that may contribute to increased cancer risk in some neighborhoods.

Funder: American Cancer Society

19-Mar-2025

Small device, big impact: Improving safety of life-saving treatments for children with leukemia

University of Houston
Peer-Reviewed Publication

Researchers at the University of Houston, in collaboration with Baylor College of Medicine, are developing new devices for treating children with hyperleukocytosis, a condition that develops when the body has an extremely high number of white blood cells, often due to leukemia.

Journal: Nature Communications

19-Mar-2025

Earliest stages and possible new cause of stomach cancer revealed

Wellcome Trust Sanger Institute
Peer-Reviewed Publication

For the first time, scientists have systematically analysed somatic mutations in stomach lining tissue to unpick mutational processes, some of which can lead to cancer. The team also uncovered hints of a potential new cause of stomach cancer that needs further research.

Journal: Nature

19-Mar-2025

TNIP1 knockdown induces the growth arrest and apoptosis of breast cancer cells by activating the NF-κB pathway

Xia & He Publishing Inc.
Peer-Reviewed Publication

Breast cancer is one of the leading causes of mortality among women worldwide. Tumor necrosis factor α-induced protein 3-interacting protein 1 (TNIP1) is a ubiquitin-binding protein that is widely expressed, but its function in breast cancer cells remains unknown. This study aimed to elucidate the molecular mechanism of TNIP1 regulation in the proliferation and apoptosis of breast cancer cells.

Journal: Oncology Advances

19-Mar-2025

NRG Oncology and Flatiron Health announce collaboration to leverage leading technology to drive more efficient clinical trials

NRG Oncology
Business Announcement

Flatiron Health, a healthtech company transforming clinical research through technology that integrates research into everyday care, today announced a collaboration with NRG Oncology (NRG), a clinical research consortium in the National Cancer Institute (NCI)’s National Clinical Trials Network (NCTN) comprised of over 1,300 worldwide research sites, to deploy Flatiron Clinical Pipe™ in a multicenter NRG clinical trial. Flatiron Clinical Pipe™, a cutting-edge electronic health record (EHR) to electronic data capture (EDC) connector, improves efficiency and reduces time and effort of clinical study data entry.

19-Mar-2025

Illuminating the immune response to aberrant DNA

University of the Basque Country
Peer-Reviewed Publication

The study, published in the prestigious journal EMBO Journal, reveals why some tumors escape the immune system, and offers a method to visualize these processes in complex biological models.

Our cells harbour a DNA detector termed cGAS to inform the immune system of viral and bacterial infections, cell death, as well as transformation during cancer. Researchers led by the Ikerbasque Research Professor Sergio P. Acebrón (University of the Basque Country and Heidelberg University) bioengineered this conserved cellular process into a novel fluorescent biosensor. The study, published in the flagship EMBO Journal, provides a multi-use biomedical tool to visualize the innate immune response to aberrant DNA across cell populations.

Journal: The EMBO Journal