Currently incurable, peripheral neuropathies are common neurological complications of chemotherapy, causing persistent pain, tingling and burning sensations in the feet and hands, sometimes even after treatment has ended. In the hope of offering a therapeutic option to affected patients, a research team led by a CNRS researcher has identified a molecule capable of preventing the onset of such side effects.

DTU researchers are behind a potentially groundbreaking antivenom that could revolutionize the treatment of venomous snakebites in Africa.

During cell division, chromosomal abnormalities – defects in chromosome number or structure – can occur, which can cause particularly aggressive forms of cancer. A new study has shed light on how chromosomal abnormalities arise in normal cells, the rates at which they do so, and how these rates are affected by various factors. To do this, the scientists developed a novel and versatile artificial intelligence (AI) tool called MAGIC, which combines automated microscopy and image analysis with single-cell genome sequencing. Understanding the molecular origins of cancer in this way could pave the way for better genetic detection tools and potential medical prevention strategies in the future.

Scientists reengineered chemo drug into spherical nucleic acids (SNAs), a globular form of DNA. Team tested the repackaged therapy on an animal model of acute myeloid leukemia, a fast-moving blood cancer. SNAs easily entered cancer cells and killed them from the inside while sparing healthy cells.