EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 22-Jun-2026 23:16 ET (23-Jun-2026 03:16 GMT/UTC)

Dana-Farber team develops open-access predictive tool to improve monitoring of smoldering multiple myeloma

Dana-Farber Cancer Institute
Peer-Reviewed Publication

Dana-Farber Cancer Institute investigators have developed an online, easy-to-use tool that more accurately predicts when a precursor blood condition called smoldering multiple myeloma is likely to turn into active cancer than existing predictive models. It identifies patients who are at a high risk of developing multiple myeloma and would benefit from treatment and enables doctors to spare those at low risk of progression from unnecessary treatment.

Journal: Nature Medicine

New lipid nanoparticle design improves precision of mRNA vaccine delivery

University of Pennsylvania School of Engineering and Applied Science
Peer-Reviewed Publication

Penn Engineers have redesigned a key component of lipid nanoparticles (LNPs), the delivery vehicles used in mRNA vaccines, to steer mRNA toward lymph nodes while reducing off-target accumulation in the liver. The modified “aroLNPs” delivered at least tenfold less mRNA to the liver than the lipid used in the Moderna COVID-19 vaccine, while preserving strong immune responses. The advance could enable more precise, lower-dose vaccines and expand the potential of mRNA therapies for cancer and autoimmune disease.

Journal: Journal of the American Chemical Society
Funder: NSF AIRFoundry, Burroughs Wellcome Fund, Cystic Fibrosis Foundation, American Cancer Society

Flexible assembly: alternative pathways in proteasome biogenesis deciphered

University of Cologne
Peer-Reviewed Publication

Study provides new insights into the processes involved in the assembly of the proteasome, a key component of cellular protein quality control that plays a significant role in ageing and diseases such as cancer and neurodegenerative disorders. The article appeared in Nature Communications and has been selected as an Editors’ Highlight.

Journal: Nature Communications

How inflammation drives bone loss in an aggressive childhood leukemia

Tokyo University of Science
Peer-Reviewed Publication

TCF3::HLF-positive B cell acute lymphoblastic leukemia is a rare and highly aggressive childhood cancer that causes severe damage to bones through mechanisms that remain unclear. To tackle this gap, researchers from Japan have developed a new mouse model that closely mirrors the disease as seen in humans. With it, they uncovered an inflammatory feedback loop that accelerates leukemia growth and bone destruction, highlighting a potential therapeutic target to combat disease progression and protect bone health.

Journal: Blood
Funder: Japan Agency for Medical Research and Development, Astellas Foundation for Research on Metabolic Disorders, Uehara Memorial Foundation, Japanese Society of Hematology, NOVARTIS Foundation (Japan) for the Promotion of Science, Princess Takamatsu Cancer Research Fund, Foundation for Promotion of Cancer Research, Cancer Research Institute, Kanazawa University, Japan Science and Technology Agency, JSI Kibou Project

Five childhood cancer research priorities receive no funding despite being chosen by children and families

University of Surrey
Reports and Proceedings

The number one research priority chosen by children with experience of cancer – making hospitals a better experience – has recently received no dedicated UK funding, according to a new report from CCLG: The Children & Young People’s Cancer Association. The report mapped childhood cancer research spending against the priorities that matter most to patients, families and professionals.

Agent Orange linked to aggressive bone marrow cancer in Vietnam veterans

University of Miami Miller School of Medicine
Peer-Reviewed Publication

Ahead of Vietnam Veterans Day on March 29, new research links Agent Orange exposure to more aggressive bone marrow cancers, identifying genetic mutations tied to earlier diagnosis and faster progression—evidence that could strengthen the case for service-connected care for aging Vietnam veterans.

Journal: Blood Advances

Immune cell ‘bloodhounds’ track cancer cells’ unique metabolic signatures, eliminate tumors in mice

Stanford Medicine
Peer-Reviewed Publication

T cells (red and blue) infiltrate cancer cells (solid blue). Engineering immune cells to track metabolites made by cancer cells improved immune infiltration, controlling or eradicating human breast tumors in mice.

Journal: Nature Immunology

Tiny sensors with the power to detect cancer

Adelaide University
Peer-Reviewed Publication

Microscopic sensors that are as thin as a strand of hair but capable of taking multiple measurements simultaneously could revolutionise the diagnosis and monitoring of diseases like cancer.

Journal: Advanced Optical Materials

Bleeding events largely outnumber thromboembolic events in patients with cancer during the last phase of life, most patients continue antithrombotic therapy

American Academy of Family Physicians
Peer-Reviewed Publication

Researchers in the Netherlands examined blood thinner use and related events in people with cancer during this period using routine general practitioner (GP) records from 2018 to 2022. They analyzed data from 2,860 adults starting when the GP first registered palliative care and reviewed records until death or their last GP visit (median follow up period was about six weeks).

Journal: The Annals of Family Medicine

Isolation and financial hardship linked with lower odds of receiving preventive health care in the U.S.

American Academy of Family Physicians
Peer-Reviewed Publication

Researchers analyzed data from the U.S. Behavioral Risk Factor Surveillance System, a national telephone survey, to better understand how social isolation and physical isolation intersect with material deprivation, including financial strain and inadequate health care access. The study examined six preventive services: COVID-19, flu and pneumococcal vaccination, and breast, cervical, and colorectal cancer screenings.

Journal: The Annals of Family Medicine