A new way to grow T cells in the lab enables them to live longer and better destroy cancer cells in a mouse model of melanoma compared to those grown in traditional growth media. The findings have the potential to greatly improve the effectiveness of cancer immunotherapies that involve taking T cells from a patient and growing them to enormous numbers in the lab before reinfusing them back into the body.

In Physics of Fluids, researchers propose a novel system that uses standing surface acoustic waves to separate circulating tumor cells from red blood cells with unprecedented precision and efficiency. The platform integrates advanced computational modeling, experimental analysis, and artificial intelligence algorithms to analyze complex acoustofluidic phenomena. The researchers included an innovative use of dualized pressure acoustic fields and strategically located them at critical channel geometry positions on a lithium niobate substrate. By means of acoustic pressure applied within the microchannel, the system design provides for the generation of reliable datasets.