The money spent to develop, test, buy and administer the first COVID-19 vaccine was more than made up for by prevented medical care and lost productivity.

Three doses of COVID-19 mRNA vaccination induce long-lasting antibody and memory B-cell responses, according to a study of 113 healthcare workers in Catalonia who were followed during three years. The study, led by ISGlobal and published in Cell Reports, also shows that exposure to the virus prior to vaccination differentially imprints the immune systems without compromising the quality of the antibody response.

Invasive species cause environmental mayhem when they establish themselves in a new ecosystem. But these interlopers can also impact human health directly. Deadly diseases can jump from animals to humans, as the COVID-19 pandemic vividly illustrated.

A novel decentralized clinical trial found that Paxlovid was ineffective in alleviating long COVID symptoms but underscored the importance of a patient-centered approach.

A new study suggests that people in their 50s and older have embraced the ability to send and receive secure medical messages with their doctors and other providers, through the digital patient portals that most health systems and medical offices now offer. The study also suggests that some older adults – including those with very low incomes – find themselves getting billed for these digital interactions.

The technology described uses a nanomechanical platform and tiny cantilevers to detect multiple HIV antigens at high sensitivity in a matter of minutes. These silicon cantilevers are cheap and easy to mass produce and can be readily equipped with a digital readout. Built into a solar-powered device, this technology could be taken to hard-to-reach parts of the world where early detection remains a challenge to deliver fast interventions to vulnerable populations without waiting for a lab.