In a new study published in Science Bulletin, researchers from West China Hospital of Sichuan University present the largest human T cell reference for 68 subtypes and states, alongside STCAT, an automated annotation tool achieving 28% higher accuracy than existing methods. Their systematic analyses reveal T cell subtype dynamics in cancer and COVID-19, offering a valuable resource for the community. They also develop a TCellAtlas database for browse T cell expression profiles and analyzing customized scRNA-seq data by STCAT tool.

In a new report released today, American Cancer Society (ACS) researchers discovered mixed progress in major cancer risk factors, preventive behaviors, and screenings in the post-COVID-19 pandemic period among adults in the United States. Smoking rates continued a long-term declining trend during the COVID-19 pandemic, but 27 million adults still smoked in 2023. Breast and colorectal cancer (CRC) screening rebounded after decreasing or stalling during the pandemic. However, past-year cervical cancer screening remained lower than pre-pandemic levels, continuing a disappointing pattern in up-to-date screening in the past two decades.

A bacteria killing coating created by scientists has been used in trials of a new paint that can be applied to a range of surfaces to effectively kill bacteria and viruses, including difficult to kill species such as MRSA, flu and COVID-19.

A new Northwestern University Feinberg School of Medicine study found virtual group singing can be an effective tool for promoting well-being and social connection during isolation. The study assessed the feasibility of virtual group singing for adults over 55 — including those with neurocognitive disorders like dementia — during the COVID-19 pandemic when older adults were experiencing health declines due to isolation. The next step in the research will be a nationwide trial funded by the National Institutes of Health Music Dementia Research Network. 

The COVID-19 pandemic has had a detrimental impact on global health. The momentous effort of researchers around the globe resulted in not only the successful development of multiple vaccines but also a vast accumulation of COVID-19 patient-derived next-generation sequencing data. Despite the availability of efficacious vaccines, COVID-19 persists, and our knowledge of host transcriptomics is still vague.

Researchers have developed a light-induced DNA detection method that enables rapid, PCR-free genetic analysis. Their technique offers ultra-sensitive mutation detection in just five minutes, reducing costs and simplifying testing. The method has significant potential in healthcare, environmental conservation, and personal health monitoring.