Breakthrough cancer therapy moves to phase 2 trials
Reports and Proceedings
Updates every hour. Last Updated: 13-Oct-2025 03:12 ET (13-Oct-2025 07:12 GMT/UTC)
Results from an early phase clinical trial presented this week at the World Conference on Lung Cancer Meeting in Barcelona, Spain, and published in the Nature Medicine journal show that patients with mesothelioma - a rare cancer of the lining of the lung that may be caused by exposure to asbestos - who received a combination of two immunotherapy drugs, nivolumab and ipilimumab, before surgery had successful surgeries and encouraging early outcomes.
A new study from the University of Missouri is helping veterinarians and pet owners better understand how to treat thyroid cancer in dogs by studying how to improve treatment with a type of therapy called radioactive iodine. It lays the important groundwork for delivering more tailored and effective treatment options.
LIFE SCIENCES
Daniele Canzio, PhD, University of California, San Francisco (Neuroscience)
Kaiyu Guan, University of Illinois Urbana-Champaign (Agriculture & Animal Sciences)
Philip J. Kranzusch, PhD, Dana-Farber Cancer Institute; Harvard Medical School (Microbiology)
Elizabeth Nance, PhD, University of Washington (Biomedical Engineering & Biotechnology)
Tomasz Nowakowski, PhD, University of California, San Francisco (Neuroscience)
Samuel H. Sternberg, PhD, Columbia University/Howard Hughes Medical Institute (Molecular & Cellular Biology)
CHEMICAL SCIENCES
Song Lin, PhD, Cornell University (Organic Chemistry)
Joseph Cotruvo, Jr., PhD, The Pennsylvania State University (Biochemistry & Structural Biology)
Frank Leibfarth, PhD, The University of North Carolina at Chapel Hill (Polymer Chemistry)
Ryan Lively, PhD, Georgia Institute of Technology (Chemical Engineering)
Leslie M. Schoop, PhD, Princeton University (Inorganic & Solid-State Chemistry)
Yogesh Surendranath, PhD, Massachusetts Institute of Technology (Inorganic & Solid-State Chemistry)
PHYSICAL SCIENCES & ENGINEERING
Charlie Conroy, PhD, Harvard University (Astrophysics & Cosmology)
Nathaniel Craig, PhD, University of California, Santa Barbara (Theoretical Physics)
Matthew McDowell, PhD, Georgia Institute of Technology (Materials Science & Nanotechnology)
Prateek Mittal, PhD, Princeton University (Computer Science)
Elaina J. Sutley, PhD, University of Kansas (Civil Engineering)
Zhongwen Zhan, PhD, California Institute of Technology (Physical Earth Sciences)
New research presented identifies interferon-induced transmembrane protein 3 (IFITM3) as a critical regulator of immunotherapy sensitivity in small cell lung cancer (SCLC), offering a promising new avenue for overcoming resistance to PD-1/PD-L1 checkpoint blockade.
The research was presented at the International Association for the Study of Lung Cancer 2025 World Conference on Lung Cancer (WCLC).
A new analysis from the PALOMA-2 study presented today shows that subcutaneous administration of amivantamab every four weeks (Q4W), in combination with daily oral lazertinib, yields a high objective response rate in patients with previously untreated EGFR-mutated advanced non-small cell lung cancer (NSCLC).
The results were presented at the International Association for the Study of Lung Cancer at the 2025 World Conference on Lung Cancer (WCLC).
A new technique has measured boron in individual cancer cells for the first time, enabling researchers to better understand how drugs act to kill tumours in some cancers, in a new article published in the Journal of Analytical Atomic Spectrometry,