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News Releases

Updates every hour. Last Updated: 21-Oct-2026 13:16 ET (21-Oct-2026 17:16 GMT/UTC)

‘Invisible’ inflammation in rare bowel disease may explain heightened colon cancer risk

Garvan Institute of Medical Research
Peer-Reviewed Publication

New research from the Garvan Institute of Medical Research has revealed for the first time that two closely related bowel diseases, currently treated in the same way, are fundamentally different. The findings help explain why one carries a much higher risk of colon cancer – and point to the need for different approaches to treatment.

Journal: Nature Communications

Physician warmth and competence may help patients worry less over normal test results

American Academy of Family Physicians
Peer-Reviewed Publication

Communicating normal test results that reveal no abnormalities isn’t always enough to ease a patient’s worries. In this study, researchers asked 349 participants to imagine having gastrointestinal symptoms and a relative recently diagnosed with bowel cancer. Participants then watched one of four videos in which a physician delivered the same identical normal test results.

Journal: The Annals of Family Medicine

The “guardian paradox” links chronic DNA damage response to aging

Impact Journals LLC
Peer-Reviewed Publication

BUFFALO, NY — September 21, 2026 — A new review was published in Volume 18 of Aging on August 31, 2026, titled “The guardian paradox: DNA damage response overactivation as an integrative driver of aging – a tumor suppressor–negative regulator framework.”

Journal: Aging-US

Dr. Laura Esserman selected as the 2026 AIM-HI Beacon Award winner for her visionary leadership in breast cancer research and care

AIM-HI Accelerator Fund
Grant and Award Announcement

Rockville, MD (21September, 2026) The AIM-HI Accelerator Fund today announces that Laura Esserman, M.D., MBA, Alfred A. de Lorimier Endowed Chair in General Surgery, Director of the University of California San Francisco (UCSF) Breast Care Center, and Professor of Surgery and Radiology at the University of California, San Francisco, is selected unanimously by the 2026 Blue Ribbon Selection Committee as the recipient of the 2026 AIM-HI Beacon Award for Women Leaders in Oncology, from a pool of outstanding global nominees.

Blood vessel features in tumors may help predict patient survival in colorectal cancer

Mass General Brigham
Peer-Reviewed Publication

Mass General Brigham researchers conducted a prospective cohort study of blood vessels in colorectal tumors, linking higher blood vessel density to lower colorectal cancer-specific mortality

Journal: JAMA Network Open
Funder: Cancer Research UK Grand Challenge Award, American Cancer Society Clinical Research Professor Award, Project P Fund, Prevent Cancer Foundation, Harvey V. Fineberg Cancer Prevention Fellowship, Brigham and Women’s Hospital Faculty Career Development Award, American Institute for Cancer Research, Uehara Memorial Foundation

Advances in lipid metabolism reprogramming in hepatocellular carcinoma

Xia & He Publishing Inc.
Peer-Reviewed Publication

Lipid metabolism reprogramming drives malignant proliferation and invasiveness in hepatocellular carcinoma (HCC). Beyond supplying energy and membrane components, lipids function as signaling molecules that modulate tumor cell epigenetics and the microenvironment. Accumulating research has clarified the implications of these metabolic alterations in HCC, providing a rationale for targeted therapies. This review summarizes key alterations in lipid metabolism within HCC and explores their mechanistic contributions to tumor progression. It further examines how lipid metabolic shifts in immune and stromal cells of the tumor microenvironment promote HCC advancement. Finally, we discuss the therapeutic potential of targeting lipid metabolism in liver cancer treatment.

Journal: Journal of Clinical and Translational Hepatology

How cells move – and how they regulate this

Helmholtz Centre for Infection Research
Peer-Reviewed Publication

The ability of cells to move and change their positions is essential for various processes in our bodies. Immune cells move to sites of action, epithelial cells migrate during wound closure and neurons wire up their axons for signal transmission over long distances, while in metastasis, cancer cells employ their motile machineries to spread throughout our bodies. A team around Prof. Klemens Rottner heading the Research Group “Molecular Cell Biology” at the Helmholtz Centre for Infection Research (HZI) has now shed new light on the central molecular interactions that accompany the formation of cytoskeletal networks at the forefront of migrating cells. Obtained insights pave the way for defining how such processes are changing in diseases and how they can potentially be modulated in the future. The results have just been published in the scientific journal Nature Communications.

Journal: Nature Communications

A new mechanism discovered that helps cells prevent errors during DNA replication

Centro Nacional de Investigaciones Oncológicas (CNIO)
Peer-Reviewed Publication

Cell division, a process fundamental to life, still holds surprises. Researchers from the University of Zurich and the Spanish National Cancer Research Centre (CNIO) have discovered a key mechanism that allows cells to protect genetic information as they divide.

The discovery centres on cohesin, a key protein involved in genome folding inside the cell nucleus.

Understanding this basic cellular process could have implications for precision oncology, as many cancer therapies work by triggering the very errors that this mechanism prevents.

Journal: Nature

Explainable AI improves prediction of lymph node metastasis in thyroid cancer

Hefei Institutes of Physical Science, Chinese Academy of Sciences
Peer-Reviewed Publication

A research team led by Prof. LI Hai from Hefei Institutes of Physical Science, Chinese Academy of Sciences, has developed an explainable artificial intelligence (AI) approach to assess the risk of central lymph node metastasis in patients with papillary thyroid carcinoma (PTC) before surgery.

Journal: Journal of Imaging Informatics in Medicine

Can vitamin C improve outcomes in people with pre-cancer blood disorders?

Wiley
Peer-Reviewed Publication

Vitamin C boosts the activity of cellular proteins called TET enzymes that help control which genes are turned on or off. Because decreased function of TET enzymes is a common driver of certain forms of blood cancer, researchers tested the effects of vitamin C supplements in patients at risk of developing such malignancies. Results of the investigators’ phase 2 clinical trial are published by Wiley online in CANCER.

Journal: Cancer

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