EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 13-Dec-2025 21:11 ET (14-Dec-2025 02:11 GMT/UTC)

An ECOG-ACRIN imaging study solves a long-standing gap in metastatic breast cancer research and care: accurately measuring treatment response in patients with bone metastases

ECOG-ACRIN Cancer Research Group
Reports and Proceedings

An ECOG-ACRIN imaging study solves a long-standing gap in metastatic breast cancer research and care: accurately measuring treatment response in patients with bone metastases. This prospective, multicenter cancer clinical trial, called FEATURE (EA1183) validated FDG-PET/CT as an improved method for predicting treatment benefits in hormone receptor-positive (HR+) metastatic breast cancer that has spread primarily or exclusively to the bones. These patients make up a large portion of individuals who are living with advanced breast cancer—yet are routinely excluded from clinical trials that rely on standard imaging-based assessments (i.e., RECIST 1.1). The study demonstrated that metabolic changes assessed by FDG-PET/CT accurately predicted progression-free survival as early as 12 weeks after treatment initiation. This trial represents a major advance in cancer imaging.

Funder: NIH/National Cancer Institute
Meeting: San Antonio Breast Cancer Symposium (SABCS)

$4.2M CDC grant to increase colorectal cancer screening in Pennsylvania

Penn State
Grant and Award Announcement

A five-year, $4.2 million grant from the Centers for Disease Control and Prevention (CDC) to the College of Medicine aims to increase colorectal cancer screening rates among communities with the greatest need. The award marks the first time an institution in the commonwealth has received funding from the CDC to support colorectal cancer screening in rural and underserved communities.

Funder: Centers for Disease Control and Prevention

Calcium in breast arteries predicts future cardiovascular disease

Penn State
Reports and Proceedings

Mammograms can detect calcium in the breast’s arteries, a sign that the blood vessels are getting stiffer. New findings from a faculty member at Penn State College of Medicine revealed that the severity and progression of calcium accumulation seen on mammograms predicted future cardiovascular disease.

Meeting: 111th Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA)

First patient in Arizona treated with new immune-cell therapy at HonorHealth Research Institute

HonorHealth Research Institute
Reports and Proceedings

A patient with synovial sarcoma, a soft-tissue cancer that usually occurs in the large joints of the arms and legs, is the first in Arizona treated with a new immune-cell-therapy known as TECELRA at the HonorHealth Research Institute.

Study implicates enzyme in neurodegenerative conditions

Oregon Health & Science University
Peer-Reviewed Publication

Researchers at Oregon Health & Science University have identified a type of enzyme with a complicated name — cell migration inducing and hyaluronan-binding protein, or CEMIP — is associated with disorders ranging from multiple sclerosis to stroke to neurodegenerative conditions like Alzheimer’s disease.

Journal: ASN NEURO

Scientists uncover key driver of treatment-resistant cancer

University of California - San Diego
Peer-Reviewed Publication

UC San Diego scientists have identified the enzyme that shatters cancer genomes and helps them evolve to resist treatment, solving a longstanding mystery in the molecular biology of cancer.

Journal: Science

MIT researchers find new way to deliver antibodies that could make treatment much easier for patients

Massachusetts Institute of Technology
Peer-Reviewed Publication

Therapeutic antibodies packaged into microparticles could be injected with a standard syringe, avoiding the need for time-consuming transfusions.

Journal: Advanced Materials
Funder: MIT Undergraduate Research Opportunities Program, U.S. Department of Energy

New FAU research strengthens evidence linking alcohol use to cancer

Florida Atlantic University
Peer-Reviewed Publication

New research delivers a timely reminder this holiday season: even moderate drinking can raise your risk for several cancers. A review of 62 studies of up to 100 million adults, found that both how often and how much you drink matter – especially for breast, colorectal, liver and digestive cancers. What you drink also matters – beer and white wine were linked to higher risks in some cases. Added dangers rose for certain racial and socioeconomic groups and from smoking, low activity, infections and poor diet.

Journal: Cancer Epidemiology

Personalised cancer medicine: New insights into the benefits and risks of therapies

Universität Leipzig
Peer-Reviewed Publication

In a translational study led by the University of Leipzig Medical Center and the Fraunhofer IZI, researchers have examined how two innovative CAR T-cell therapies targeting the B-cell maturation antigen perform in patients with hard-to-treat multiple myeloma. Their aim was to determine which molecular mechanisms influence the therapeutic success of such living, cell-based therapies in this blood cancer. The findings have been published in the renowned journal Cancer Cell. The Leipzig research team led by Professor Maximilian Merz and Dr Kristin Reiche has now secured a further two million euros in funding for a new project to advance the development of next-generation immunotherapies for multiple myeloma.

Journal: Cancer Cell

Preoperative radiation may improve antitumor immune response in most common form of breast cancer

American Association for Cancer Research
Reports and Proceedings

Preoperative radiation improved T-cell infiltration (TCI) in patients with hormone receptor (HR)-positive, HER2-negative breast cancer when administered in combination with pembrolizumab (Keytruda) and chemotherapy and led to improved treatment responses prior to surgery, according to the results of the phase II P-RAD clinical trial presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

Meeting: San Antonio Breast Cancer Symposium (SABCS)

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