BUFFALO, NY — October 16, 2026 — A new research paper was published in Volume 13 of Oncoscience on September 24, 2026, titled “Investigating the role of 3D goggles in optimising time during deep-inspiratory breath-hold radiotherapy: A randomised study.”

WPI researchers, who are developing a tool to analyze skin images for signs of skin cancer, have finished third in an international artificial intelligence (AI) competition aimed at improving early diagnosis of melanoma, a potentially lethal type of skin cancer.

Hepatocellular carcinoma (HCC), the most common type of primary liver cancer, is characterized by high mortality and limited treatment options. A new review published in the Chinese Medical Journal provides a comprehensive overview of how two key cancer hallmarks—epigenetic regulation and metabolic reprogramming—interact to drive HCC progression. The review highlights the bidirectional crosstalk between these processes and explores how targeting this axis could open new avenues for therapy.

Protein glutamylation is a reversible post-translational modification regulating protein activity, stability, localization, and interactions. Once considered part of the tubulin code, it is now recognized as a broader signaling mechanism. This review summarizes TTLL/CCP enzymes; roles in cilia, neurodevelopment, cell division, and cytoskeleton; and nontubulin substrates including cGAS, KLF4, IL-7Rα, BAP1, TAB1, and YAP1, which affect immunity, cell fate, metabolism, tumor progression, and immune evasion. It proposes glutamylation as a versatile signaling-related PTM and discusses therapeutic and biomarker opportunities.

Researchers at the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University have developed a way to observe how antibodies interact with a cancer-related protein carried on tiny membrane-bound vesicles released by cells. Using high-speed atomic force microscopy, they found that measuring how much of the protein is present does not necessarily show how accessible it is to antibodies. The findings reported in the journal Small Methods provide a new way to investigate differences between individual cancer-derived vesicles although further research is needed before the approach can be used clinically.

A world-first study by Australian researchers compared three mRNA-LNP vaccine platforms in human blood samples, generating findings that could revolutionise cancer treatment and vaccine design.

Molecular imaging with ⁶⁸Ga-HER2 PET/CT may provide an early, targeted measure of how well treatment is working in patients with HER2-positive breast cancer. According to new research published in the October issue of The Journal of Nuclear Medicine, ⁶⁸Ga-HER2 PET/CT can detect changes in HER2-positive breast cancer after only two cycles of neoadjuvant treatment, enabling physicians to potentially provide information that could support earlier discussions about subsequent treatment and surgical planning.

Exposure to common chemicals may alter how normal human breast tissue develops, according to a new study. The findings suggest that exposure to some chemicals—particularly multiple bisphenols at once—may create molecular changes in breast tissue that could influence susceptibility to breast disease later in life.

Overall ultra-processed food (UPF) consumption was not associated with increased colorectal cancer (CRC) incidence in a cohort of more than 400,000 U.S. adults, according to a study published October 15^th by Erikka Loftfield of the National Cancer Institute, U.S., and colleagues in the open access journal PLOS Medicine.

A study conducted at the Hubrecht Institute reveals that the intestines use the rhythm of a signal to decide which cells to make. Researchers from the Sonnen group discovered that chemical signals oscillate at different rhythms in different cells of the small intestine. In a new study published in Science, they show that altering the frequency of these oscillations changes the balance of cell types that form. The findings may improve our understanding of how tissues maintain a healthy cell type balance and how disrupted signaling dynamics contribute to conditions such as inflammation and cancer.