First author on the QUT-led, multinational study published in Nature Communications, Brisbane’s Translational Research Institute-based Dr Srilakshmi Srinivasan, from QUT’s School of Biomedical Sciences, said the researchers studied the role of a particular prostate cancer genetic variation or SNP.

The largest ever clinical trial of T cell therapy (a type of cell-based immunotherapy) for solid tumours has been completed.

Led by a Singapore clinician-investigator, the global, international, multisite trial recruited 330 advanced nasopharyngeal (NPC) cancer patients in 23 sites across Singapore, Malaysia, Thailand, Taiwan and the United States.

The trial did not show an overall survival benefit for the entire patient cohort but a subset analysis combining outcomes of US, Singapore and Taiwanese sites, showed better progression free survival and overall survival.

Results suggest that T cell therapy success would be enhanced by identifying the biomarkers in patients and within the cell therapy, to guide precision delivery.

A Cancer Research UK-funded trial is giving participants resveratrol as a potential prevention drug for bowel cancer. Resveratrol is a chemical mostly found in red grapes and products made from these grapes, such as wine and juice. Previous lab studies have shown that low doses of purified resveratrol can reach the bowel undigested and inhibit bowel cancer growth.

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

This special edition features upcoming oral presentations by MD Anderson researchers at the 2024 Society for Immunotherapy of Cancer (SITC) Annual Meeting, providing new insights into the tumor microenvironment and showcasing immunotherapy advances across a variety of cancer types. All SITC content from MD Anderson can be found at MDAnderson.org/SITC.

A Michigan State University researcher’s new model for studying breast cancer could help scientists better understand why and where cancer metastasizes.