The Damon Runyon Cancer Research Foundation and St. Jude Children’s Research Hospital have announced their newest class of pediatric cancer research fellows, each of whom will receive funding for four years ($300,000 total) to support an innovative research project with the potential to significantly impact the diagnosis or treatment of one or more pediatric cancers.

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup. Researchers at RPTU University Kaiserslautern-Landau, Southwest Germany, have now helped to elucidate the molecular mechanisms involved. The findings could be an important milestone in the development of targeted cancer therapies.

The leading nonprofit Colorectal Cancer Alliance (Alliance) is making bold strides in its mission to put an end to the disease. Its Project Cure CRC research initiative awarded new grants, convened top scientists to spark breakthrough advancements at its Cure CRC Summit, and unveiled K-SPY, a groundbreaking multi-center platform trial for high-risk colorectal cancer cases. Since its launch, Project Cure CRC has received 275 proposals, of which 22 have been approved totaling $10.5 million in awards. The latest awards reflect $2.8 million of the overall funding for urgently needed innovations. With significantly more funds available, the Alliance issues a renewed Project Cure CRC Request for Proposals from researchers with cutting-edge colorectal cancer studies.

New research from Memorial Sloan Kettering Cancer Center (MSK) supported the approval of a new treatment for ER-positive, HER2-negative advanced breast cancer; suggests a new strategy for overcoming resistance to Akt inhibitors in patients with PTEN-mutated prostate cancers; provides new understanding of B cell lymphomas that could lead to new treatments; examines using ChatGPT to help capture patient-reported outcomes; and developed the first customizable, scalable model for palliative care training for emergency departments.

A new blood test could help doctors detect pancreatic cancer earlier, potentially improving survival rates for one of the deadliest cancers.