Blood removal before major liver surgery cuts transfusions in half
Peer-Reviewed Publication
Updates every hour. Last Updated: 30-Apr-2025 06:08 ET (30-Apr-2025 10:08 GMT/UTC)
Metastasis is responsible for 90 percent of cancer deaths. Researchers have found that the mutations driving it may stem from a commonly inherited variant of the PCSK9 gene.
For the first time, researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM) to accurately model a patient’s response to CAR T cell therapy in real time. The organoid’s response to therapy mirrored the response of the actual tumor in the patient’s brain. That is, if the tumor-derived organoid shrunk after treatment, so did the patient’s actual tumor.
Researchers at Karolinska Institutet and the University of Gothenburg have identified two types of metabolic-associated fatty liver disease – a liver-specific type and a systemic type that affects other organs and tissues. The discovery could lead to improved diagnosis and treatment of this growing patient group. Two studies are published back-to-back in Nature Medicine.