Bone marrow cell atlas for improved leukemia research
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Jun-2026 19:15 ET (22-Jun-2026 23:15 GMT/UTC)
A study co-led by University of Texas at Dallas bioengineers identified a distinctive feature of tissues from young patients diagnosed with colorectal cancer, a disease that typically affects older patients.
Researchers found that both cancerous and noncancerous colon tissue was mechanically stiffer in younger patients with respect to older patients diagnosed with colorectal cancer. The findings, published in the Jan. 30 print edition of Advanced Science, suggest that stiffness may create an environment that promotes the development of colorectal cancer in people under the age of 50. This work may offer new approaches for preventing and treating this disease — known as early-onset colorectal cancer — a condition that has been mysteriously rising over the past 30 years.
Patients with triple-negative breast cancer have different treatment responses
Computational tools that predict treatment response historically overlook gene expression changes relative to the tumor microenvironment
New computational approach outperformed current methods for predicting chemotherapy response in patients with triple-negative breast cancer
Biomarker also directs some patients to alternative therapy and highlights population-specific differences between Asian and European tumors
In the most recent of a series of four studies featured in Bone Marrow Transplantation, researchers have found that a highly sensitive DNA-based test can help doctors predict which patients with acute myeloid leukemia (AML) are most likely to relapse.