Fluorescence navigation is a novel technique for accurately identifying hepatocellular carcinoma (HCC) lesions during hepatectomy, enabling real-time visualization. Indocyanine green-based fluorescence guidance has been commonly used to demarcate HCC lesion boundaries, but it cannot distinguish between benign and malignant liver tumors. This review focused on the clinical applications and limitations of indocyanine green, as well as recent advances in novel fluorescent probes for fluorescence-guided surgery of HCC. It covers traditional fluorescent imaging probes such as enzymes, reactive oxygen species, reactive sulfur species, and pH-sensitive probes, followed by an introduction to aggregation-induced emission probes. Aggregation-induced emission probes exhibit strong fluorescence, low background signals, excellent biocompatibility, and high photostability in the aggregate state, but show no fluorescence in dilute solutions. Design strategies for these probes may offer insights for developing novel fluorescent probes for the real-time identification and navigation of HCC during surgery.

The University of Texas MD Anderson Cancer Center today announced a $9 million gift from the F. W. Bert and Mae Dean Wheeler Foundation to establish the F. W. Bert and Mae Dean Wheeler Nurse Leadership Academy. The Wheeler Foundation’s gift supports MD Anderson’s innovative efforts to cultivate the next generation of oncology nurse leaders as part of the Meyers Institute for Oncology Nursing. The Wheeler Nurse Leadership Academy will focus on providing the coaching and mentoring infrastructure to ensure nurses are equipped with the unique skills to position them as successful leaders.

Moffitt Cancer Center has become the first standalone cancer center in the world to open a Nikon Center of Excellence. This prestigious achievement highlights Moffitt’s commitment to cutting-edge imaging technology and groundbreaking cancer research.

Fred Hutch Cancer Center announced 10 recipients of the annual Harold M. Weintraub Graduate Student Award, which recognizes the exceptional achievements of graduate studies in the biological sciences.

While the human papillomavirus (HPV) is most associated with cervical cancer risk and women, a new survey commissioned by The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) shows that the majority of people are unaware that the virus is actually more common among men than women and is associated with rising rates of other cancers that directly impact men.