‘Undruggable' cancer-driving proteins resist various treatments because drugs cannot bind to them. New Velcro-like polymer grabs proteins without needing a traditional binding pocket. Polymers also grab the cell’s waste-disposal machinery, bringing it to the protein. Strategy worked in cellular cultures and animal models of cancer for two notoriously undruggable proteins.

A study led by researchers from the A*STAR Genome Institute of Singapore (A*STAR GIS), together with the National Cancer Centre Singapore (NCCS), Singapore General Hospital (SGH), and KU Leuven, Belgium, has uncovered why some colorectal cancer cells become harder to treat and more likely to spread after chemotherapy. Published in Nature Cell Death & Disease, the findings reveal a biological “survival shift” that helps cancer cells withstand treatment and move more aggressively, and point to new ways to identify high-risk patients and potentially improve future treatment strategies.

Small fragments of plastic were found in nine out of 10 patients with prostate cancer, and in higher levels inside tumors than in nearby noncancerous tissue, a new study finds.

Ochsner MD Anderson Cancer Center at The Gayle and Tom Benson Cancer Center in New Orleans announces a milestone in advanced cancer treatment, as the first institution in Louisiana to provide an adult patient with tumor-infiltrating lymphocytes (TIL) therapy for advanced melanoma.  

Scientists have developed an adaptable materials platform that can safely and efficiently deliver a wide range of genetic medicines, a breakthrough that could accelerate the development of next‑generation vaccines, cancer treatments, and gene‑silencing drugs.