Data was used from Veterans Affairs health system

Patients who were retreated with docetaxel had longer overall survival compared with those who switched to cabazitaxel

Findings were published in JAMA Network Open

University of Missouri researchers have released the world’s largest collection of protein models with quality assessment — a groundbreaking new resource that could accelerate drug development for diseases such as Alzheimer’s and cancer. The database, called PSBench, includes 1.4 million annotated protein structure models, all verified by independent experts. It gives scientists the reliable information they need to build more accurate artificial intelligence (AI) systems for assessing the quality of protein structure models, which is critical for developing future medical treatments.

Researchers at Case Western Reserve University have discovered a way to breach one of cancer’s most stubborn defenses: the impenetrable fortress that solid tumors build around themselves. By injecting nanobubbles filled with inert gas into tumors and “jiggling” them with ultrasound, the team successfully broke down tumor barriers enough for treatment-bearing molecules to get inside, according to results of a new study published in ACS Nano.

Oral cancers with a high risk of recurrence can be identified at an early stage by examining the lymphatic vessels of the tumor. Finnish researchers have discovered for the first time that the surface cells of the lymphatic vessels in oral cancer contain proteins that indicate cell division and strongly predict disease progression and mortality.

Postpartum breast cancer is diagnosed five to ten years after giving birth. It is associated with a higher risk of metastasis and a lower survival rate compared with women who have not been pregnant or those diagnosed during pregnancy. A team from the Institut Pasteur set out to understand the mammary gland mechanisms involved in tumor formation during involution, a major tissue remodeling process that occurs after pregnancy. In a preclinical study the scientists reveal how senescence, a cellular response inducing stable cell cycle arrest, plays an ambivalent role during mammary gland involution. While it is crucial for the normal tissue remodeling process in the mammary gland, senescence can also be hijacked by tumor cells to help them spread. This discovery, published in Nature Aging on February 18, 2026, suggests that targeting senescent cells during mammary gland involution could reduce the risk of postpartum breast cancer.