A new gene therapy has been used to successfully treat a deadly childhood liver disease using mice that model this disease by researchers at UCL and Great Ormond Street Hospital.

For some people, cancer immunotherapies are life-changing. These treatments can turn the body’s own immune system against a tumor, either eliminating it or shrinking it enough to make surgery possible. But these therapies don’t work for everyone, can gradually stop working or can come with a host of side effects, including severe inflammation. A new experimental therapy aims to change that. Scripps Research scientists are testing SAR’877, a bispecific molecule designed to restore immune cells’ ability to fight cancer.