MSK Research Highlights, March 27, 2026
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Jun-2026 17:15 ET (22-Jun-2026 21:15 GMT/UTC)
Scientists at UPMC Hillman Cancer Center and the University of Pittsburgh School of Medicine developed BiliSeq, a molecular test that detected bile duct cancer with twice the sensitivity of the standard test, giving physicians a more accurate picture of the patient’s diagnosis.
Chinese researchers identified tumor-specific MHC-II (tsMHC-II) expression as a novel biomarker predicting response to neoadjuvant immunotherapy in gastric cancer. Single-cell profiling revealed higher MHC-II expression in tumor cells from treatment-sensitive patients. Validated in prospective trials, tsMHC-II-positive patients achieved 36.67% pathological complete response rate versus low rates in unselected populations. This simple immunohistochemistry-based biomarker outperforms current PD-L1 assessment and could guide personalized therapy for gastric cancer patients.
This article explores recent advances in liposomal nanotechnology for photodynamic therapy, showing how improved drug loading, targeting, and light-activated efficiency are enhancing cancer treatment outcomes.
Malignant gliomas are among the deadliest brain cancers, with limited treatment options and poor survival. A new comprehensive review analyzes decades of global clinical data on boron neutron capture therapy (BNCT), a targeted radiation approach. The study finds consistent survival benefits across multiple tumor types and treatment settings. By synthesizing evidence from accelerator- and reactor-based studies worldwide, the work highlights BNCT's renewed clinical promise and outlines key challenges for broader adoption.