A large, long-term study led by an Albert Einstein College of Medicine researcher has found that the introduction of the human papillomavirus (HPV) vaccine in community settings is highly effective in protecting young women from infections caused by the cervical-cancer-causing virus—including women who didn’t even receive the vaccine. The study was published today in JAMA Pediatrics.

A team of researchers led by Rice University, in collaboration with colleagues in Mozambique and The University of Texas MD Anderson Cancer Center, has developed a simple, affordable human papillomavirus (HPV) test that delivers results in less than an hour with no specialized laboratory required. The breakthrough could provide an option for women in low-resource settings to be screened and treated for cervical cancer in a single clinic visit, a step that global health experts say could save countless lives. The research was recently published in Nature Communications.

The most common type of liver cancer in children, hepatoblastoma, surprisingly appears to contain many immune cells from a type that has long been overlooked. This is according to a study by researchers at the Princess Máxima Center and UMC Utrecht. The discovery of these myeloid cells in liver tumors unveils new avenues for treatment. 

In tissue biopsies, cancer cells are frequently observed to have nuclei (the cell's genetic information storage) larger than normal. Until now, this was considered a sign that the cancer was worsening, but the exact cause and effect had not been elucidated. In this study, the KAIST research team found that cancer cell nuclear hypertrophy is not a cause of malignancy but a temporary response to replication stress, and that it can, in fact, suppress metastasis. This discovery is expected to lead to the development of new diagnostic and therapeutic strategies for cancer and metastasis inhibition.