In 94,344 UK Biobank participants, accelerometry objectively classified 24-hour rest-activity timing phenotypes. Over a median 6.8 years, the night-active phenotype was associated with higher incident MDD and anxiety risk, while an early-morning-active phenotype was associated with lower MDD risk.

The findings offer association evidence and exploratory MRI clues, but they do not establish that changing activity timing prevents mental disorders. Randomized trials are needed.

Prof. Yingxiang Liu's team at the State Key Laboratory of Robotics and Systems, Harbin Institute of Technology, developed a unique tripodal piezoelectric robot driven by a high-stiffness ring-shaped elastic body. By combining axisymmetric vibration modes with an asymmetric foot arrangement, the proposed robot achieves both planar agile motions and high load capacity.

Hybrid-polarimetric radar promises a wider view of Earth with less data burden, but scientists have long needed real satellite evidence to show where this streamlined mode can rival fuller polarimetric systems—and where it falls short.

The team constructed a hierarchical “herb–compound–target–disease” network that aligns with the holistic philosophy of TCM. This paradigm upgrades TCM intervention from single‑target modulation to network target regulation, scientifically interpreting the molecular logic of the “monarch‑minister‑assistant‑guide” compatibility principle and syndrome differentiation. It builds a foundational bridge between classical TCM theory and modern molecular biology.