Live imaging captures DNA folding in sperm cells for the first time
Peer-Reviewed Publication
Updates every hour. Last Updated: 26-Apr-2025 12:08 ET (26-Apr-2025 16:08 GMT/UTC)
Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University and colleagues have achieved a major breakthrough in understanding sperm DNA packaging. Using high-speed atomic force microscopy (HS-AFM), they captured the real-time process of protamine (PRM)-induced DNA condensation, providing critical insights into fertility, genome stability, and future applications in medicine. Their findings are published in Nucleic Acids Research.
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