Treatment Algorithm for Stage IV NSCLC Patients (IMAGE)
Caption
ALK: Anaplastic lymphoma kinase; BRAF: B-raf proto-oncogene, serine/threonine kinase; CDK: Cyclin-dependent kinase; EGFR: Epidermal growth factor receptor; JAK: Janus kinase; MEK: Mitogen-activated protein kinase kinase; MET: Mesenchymal-epithelial transition factor; mTOR: Mechanistic target of rapamycin; NSCLC: Non-small cell lung cancer; PI3K: Phosphoinositide 3-kinase; RET: Rearranged during transfection; ROS1: C-ros oncogene 1; STAT: Signal transducer and activator of transcription; TKI: Tyrosine kinase inhibitor.
Credit
: Prof. Yuankai Shi from National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College Image source link: https://journals.lww.com/cmj/fulltext/2026/04050/epidermal_growth_factor_receptor_tyrosine_kinase.2.aspx
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