Proteomic analysis and glucose metabolism in the heart (IMAGE)
Caption
(A) Proteomics protein identification and quantitative results statistics. (B) A Venn diagram showed the overlapping differentially expressed proteins between the RCM group and the WT group. (C) The principal component analysis of all samples. (D) GO annotation statistics of differentially expressed proteins in the RCM_vs_WT group. The ordinate represented the secondary GO function annotation information, including biological processes, molecular functions, and cell components, which were successively distinguished by blue, red, and orange. The abscissa indicated the number of differentially expressed proteins in each functional category. (E) KEGG enrichment analysis, top20 KEGG TopMapStat sorted by the number of proteins enriched on the KEGG pathway, and up-down-regulation analysis of KEGG enrichment pathway. The blue represents down-regulation and the red represents up-regulation. (F) Glucose content in heart tissue (n = 3). (G) Lactic acid content in heart tissue (WT, n = 5; cTnI193His-M, n = 4). ∗∗P < 0.01.
Credit
Min Luo, Lingjuan Liu, Wenjing Yuan, Junjun Quan, Mi Li, Jie Tian
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