Impact of dietary convergence on microbiome diversification. (IMAGE)
Caption
(A) Principal coordinate analysis representing quantitative genus-level microbiome variation (n=381; Bray-Curtis dissimilarity). Arrows on the plot indicate direction and relative magnitude of shifts observed between baseline and intervention (dietary convergence) vs intervention and follow-up (dietary divergence). Microbiome community-type distribution is shown on the insert. Boxplots below axis 1 show the distribution of microbiomes belonging to the different study phases along the principal axis of variation. (B) Distance-based redundancy analysis of the association of potential covariates with quantitative genus-level microbiome variation (n=294). Transparent bars correspond with covariates that, while displaying a significant association in a univariable model, did not contribute significantly to microbiome variation in the stepwise variant. Bact1, Bacteroides1; Bact2, Bacteroides2; HbA1c, haemoglobin A1C; HDL, high-density lipoprotein; Prev, Prevotella; Rum, Ruminococcaceae.
Credit
By Astrid Vermeulen, Erik Bootsma, Sebastian Proost, et al.
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Credit must be given to the creator. Only noncommercial uses of the work are permitted.
License
CC BY-NC