Microbiome variation associated with dietary convergence. (IMAGE)
Caption
(A) Boxplot comparing faecal microbial load variation over study phases. Load decrease during the intervention period (n=266; Kruskal-Wallis with post hoc Dunn test). (B) Weighted distribution of community-type prevalence over study phases. Bact2 prevalence increased significantly on dietary convergence (n=266; online supplemental figure 9). (C) Boxplot representing Faecalibacterium abundance distribution over study phases. A decrease in the abundance was observed during the intervention period (n=266; Kruskal-Wallis with post hoc Dunn test). (D) Boxplot presenting quantitative microbiome variance observed before/after (baseline and follow-up combined) and during the intervention period. Variance significantly increased during the intervention (n=266; dispersion test on Bray-Curtis dissimilarities at genus level). (A–D) Analyses performed excluding lag samples. (A,C,D) The body of the boxplot represents the first and third quartiles of the distribution, with the median line and the whiskers extend from the quartiles to the last data point within 1.5 times IQR, with outliers beyond. *adjP<0.05, **adjP<0.001. adjP, adjusted p value; Bact1, Bacteroides1; Bact2, Bacteroides2; IQR, interquartile range; Prev, Prevotella; Rum, Ruminococcaceae.
Credit
By Astrid Vermeulen, Erik Bootsma, Sebastian Proost, et al.
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License
CC BY-NC