CD8 TE cell demonstrates CML-specific gene expression. (IMAGE)

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CD8 TE cell demonstrates CML-specific gene expression.

Caption

(A) The volcano plot showing differential genes of CD8 TE cells between CML and healthy controls. (B) The Venn diagram showing the overlap of up-regulated genes in CD8 TE and CD8 T cells in CML. (C) The Venn diagram showing the overlap of down-regulated genes in CD8 TE and CD8 T cells in CML. (D) The bubble plot showing the biological function enrichment of differential genes in CD8 TE cells. (E) The boxplots showing the differential gene expression between clinical newly diagnosed CML patients, CML patients in remission, and healthy samples based on bulk RNA sequencing data. (F) The violin plot showing the gene expression in T cell subsets between CML and healthy samples. CML, chronic myeloid leukemia; TE, terminal effector.

Credit

Chenjian Zhuo, Xin Dong, Xueya Zhao, Weiru Wu, Hao Zhou, Jing Feng, Lingbo Liu, Mingqian Feng, Chunjiang He, Yu Hou

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