New ‘smart’ nanoparticles help the immune system better attack tumours
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Updates every hour. Last Updated: 19-Oct-2026 16:16 ET (19-Oct-2026 20:16 GMT/UTC)
New study finds that widespread underreporting of Covid-19 deaths cannot be explained simply by differences in countries’ ability to count and record deaths. Across 134 countries and territories, an estimated 45%–55% of governments misreported Covid mortality, with underreporting far more common than overreporting. The study provides comparable country-level data of the extent of misinformation for researchers and policymakers. The findings point to a broader lesson beyond the pandemic: strong institutions and an informed public can play an important role in protecting the reliability of official information.
**Note this is an early release from the Annual Meeting of the European Association for the Study of Diabetes [EASD]. Please credit the meeting when using this research**
New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) shows that people who have had COVID-19 have a lower, rather than higher, risk of subsequent development of type 1 diabetes (T1D). Furthermore, the effect is evident only in people who did not receive the SARS-CoV-2 vaccine. The study is by Carl Villaro Nolsøe and Dr Runa Mortansdottir Nolsöe, North Zealand Hospital, Hillerod, Denmark, and colleagues.
New research reveals a shared biology behind profound fatigue in five major illnesses - including long Covid and PTSD.
A new paper shows striking biological similarities between five major illnesses which until now have largely been viewed as separate disorders.
The findings suggest that chronic fatigue syndrome (also known as ME), long Covid, post-traumatic stress disorder (PTSD), rheumatoid arthritis and multiple sclerosis (MS) may be driven by common underlying mechanisms.
This is despite the conditions being triggered by different events - ranging from viral infections to psychological trauma or autoimmune responses.
A comprehensive in silico scan of human respiratory viruses identified 3CLpro cleavage motifs within influenza NP and PA. Experimental validation confirmed that 3CLpro-mediated cleavage triggers rapid protein degradation and cytoplasmic mislocalization. Consequently, both ectopic 3CLpro expression and SARS-CoV-2 replication effectively inhibit replication across diverse influenza virus strains, revealing a broad-spectrum antiviral mechanism.
Six years after COVID-19 disrupted childhood around the world, new research following the same children from before the pandemic through today finds that the damage was far less widespread than early warnings predicted. A Special Section in the Society for Research in Child Development's flagship journal Child Development, synthesizing 17 long-term studies across six countries, finds that most children's health, learning, social development, and wellbeing recovered substantially. Setbacks that persisted were concentrated among children who already faced other risks before the pandemic began. This new research, tracking children over a longer period, tells a different story: pandemic impacts were real and wide-ranging, but not as severe as initially feared, and many effects weakened over time. The children who fared worst and recovered more slowly were disproportionately those shaped by pre-existing risks — not the pandemic alone.
Results from a clinical trial funded by the National Institutes of Health (NIH) and published today in the journal Lancet Infectious Diseases show that the antiviral drug, PAXLOVID, commonly prescribed to treat acute COVID-19, does not have an impact on Long COVID symptoms when compared to placebo.
More than two-thirds of hospitalized COVID-19 survivors maintained stable cognition 2 years after Omicron infection, while one in five experienced reversible decline. Researchers report that only 10.8% developed irreversible cognitive decline, including 3.6% with progressive decline. Older age, reinfection, severe illness, hypertension, longer hospitalization, and white matter lesions increased the risk, while education and vaccination were protective. Findings highlight potential for cognitive recovery, supporting monitoring of patients at higher risk of progressive decline.
Inspired by the work of the RNA Therapeutics Institute at UMass Chan Medical School and the development of the COVID vaccine, UMass Chan scientistis Marcus Ruscetti, PhD, and Chaitanya Naimesh Parikh, PhD’26, have developed an immunotherapy using a cocktail of messenger RNAs (mRNA) that could potentially be transformative for pancreatic cancer treatment.