Researchers have uncovered a surprising layer of complexity in aldosterone-producing adenomas—adrenal gland tumors that drive high blood pressure. Using cutting-edge analysis techniques, they discovered that these tumors harbor at least four distinct cell types, including ones that produce cortisol, the body’s main stress hormone. Published in PNAS, their findings not only explain why some patients with these tumors develop unexpected health issues, like weakened bones, but also pave the way toward new treatment strategies.

In metastatic cancer surveillance, monitoring the actual concentrations of circulating tumor DNA (ctDNA) may be critical. Researchers showed that absolute ctDNA concentration thresholds can be defined to rule out or predict impending cancer progression. They introduce a dual threshold model in a novel study in The Journal of Molecular Diagnostics, published by Elsevier, that may improve cancer surveillance, patient stratification, and risk-informed, personalized treatment by providing more accurate and timely assessment of disease progression.

A study published today from the University of Kansas in the Journal of Food Composition and Analysis shows most infant formulas on the U.S. market contain primarily added sugars rather than the healthier, naturally occurring lactose found in cow-milk base that would be best for babies because it’s closest to human breast milk.

Researchers have developed a cancer vaccine method that can target virtually any solid tumor, amplifying the visibility of tumor antigens to the immune system, leading to a potent response. Preclinical tests shows that it helps slow or stop the progression of melanoma, triple-negative breast cancer, lung and ovarian cancer

BUFFALO, NY – February 24, 2025 – A new research paper was published in Oncotarget, Volume 16, on February 18, 2025, titled “Robust p53 phenotypes and prospective downstream targets in telomerase-immortalized human cells.”

Despite its crucial role in interventional therapies for liver malignancy, cone-beam computed tomography (CBCT) has not yet been fully integrated into clinical practice due to several complicating factors, including nonstandardized operations and limited recognition of CBCT among interventional radiologists. In response, the Chinese College of Interventionalists has released a consensus statement aimed at standardizing and promoting the application of CBCT in the interventional therapies for liver malignancy. This statement summarizes CBCT scanning techniques, and operational standards, and highlights its potential applications in clinical practice.

The Technion researchers’ paper reveals the answer through a phenomenon they discovered: the key to nanoparticle transport across the intestinal wall lies in breast milk proteins, which create an effect that named by the Technion scientists - Human Breast Milk Protein Corona. This "corona" forms a protein coating around the nanoparticle, allowing it to pass through the intestinal layers, and depends on the nanoparticles’ charge. The researchers confirmed their findings in both human intestinal cell line and pig intestinal samples.