New insights into MYH9 reveal expanding role in cancer and genetic disorders
Peer-Reviewed Publication
Updates every hour. Last Updated: 23-Oct-2026 22:16 ET (24-Oct-2026 02:16 GMT/UTC)
A comprehensive new review article highlights the growing importance of the MYH9 gene as a central player in both cancer biology and inherited genetic conditions, offering fresh perspectives on its potential as a therapeutic target.
A growing body of evidence is reshaping how cancer is understood, placing the spotlight on intra-tumoral microbiota as powerful yet previously overlooked players within the tumor microenvironment. Far from being sterile, tumors host complex communities of bacteria, fungi, and viruses that actively influence disease progression, immune responses, and treatment outcomes.
A comprehensive new review highlights the growing importance of FOXK2, a versatile transcription factor, in shaping cancer behavior and influencing clinical outcomes across a wide range of tumor types. The article brings together emerging knowledge to clarify how this gene functions in cancer and why it is attracting increasing attention as a potential diagnostic and prognostic marker.
Researchers at Baylor College of Medicine have developed a drug called CS18 that disrupts the ability of cancer cells to survive therapy. The findings support exploring the possibility of using CS18 to treat human cancer in the future.
DepMap scientists have generated dependency data on nearly 150 three-dimensional cancer cell models across 10 cancer types.
The updated catalog reveals cancer phenotypes, cell states, and gene dependencies that are missed in traditional cell lines and shows that both model types are complementary because each captures biology that the other misses.
The integration of data on 2D and 3D models creates a more comprehensive DepMap, moving the resource towards its goal of capturing the complete landscape of cancer vulnerabilities.