A fundamentally new therapeutic approach to cystic fibrosis: Nanobody repairs cellular defect
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Jun-2026 23:16 ET (23-Jun-2026 03:16 GMT/UTC)
A tiny antibody component could fundamentally transform the treatment of cystic fibrosis: For the first time, researchers have succeeded in developing a so-called nanobody that penetrates directly into human cells and can repair the chloride channel most commonly affected in cystic fibrosis. The innovative therapeutic approach was developed in collaboration between teams from Charité – Universitätsmedizin Berlin and the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP). The results have now been published in the journal Nature Chemical Biology*.
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