EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 14-Dec-2025 13:11 ET (14-Dec-2025 18:11 GMT/UTC)

New antibody restricts the growth of aggressive and treatment-resistant breast cancers

King's College London
Peer-Reviewed Publication

A new potential antibody therapy strategy which restricts the growth of treatment-resistant breast cancers has been developed.

Journal: Cancer Research

Hidden immune defense mechanism could be used to fight cancer, says study

Temple University Health System
Peer-Reviewed Publication

In a recent study published in the journal Nature, researchers at Fox Chase Cancer Center have uncovered a new mechanism by which the body’s immune system responds to viral infections, a finding that can potentially be harnessed to attack cancer.

Journal: Nature

High levels of specific protein may impair high-risk paediatric neuroblastoma

Umea University
Peer-Reviewed Publication

High levels of a specific protein can reduce the growth of tumour cells in neuroblastoma, a form of cancer that affects the sympathetic nervous system in young children. This is shown in a new study by researchers at Umeå University and Karolinska Institutet, Sweden. The protein in question also seems to cause the cancer cells to change into less aggressive cells

Nanoparticle blueprints reveal path to smarter medicines

University of Pennsylvania School of Engineering and Applied Science
Peer-Reviewed Publication

Researchers at the University of Pennsylvania, Brookhaven National Laboratory, and Waters Corporation have revealed that lipid nanoparticles (LNPs) — the delivery vehicles for RNA therapies — come in a surprising range of shapes and structures. Reported in Nature Biotechnology, the study shows that these structural differences directly influence how well LNPs deliver their therapeutic cargo, offering a blueprint for tailoring nanoparticles to specific diseases. The findings open the door to a new era of precision design for RNA medicines, moving beyond today’s trial-and-error approach.

Journal: Nature Biotechnology
Funder: DOE/US Department of Energy, American Cancer Society, U.S. National Science Foundation, Burroughs Wellcome Fund

Colon cancer DNA detectable in blood can guide chemo decisions: study

Walter and Eliza Hall Institute
Peer-Reviewed Publication

An international study has found a simple blood test could change how doctors decide which patients with colon cancer need chemotherapy and the patients that can be safely spared. The blood test is the result of a collaboration between Autralian medical research institute WEHI and the Johns Hopkins Kimmel Cancer Centre.

Journal: Nature Medicine

Drug which stops tumors' blood supply could help kids with bone cancer live longer

Frontiers
Peer-Reviewed Publication

Survival rates for children with multi-metastatic Ewing’s sarcoma — a kind of bone cancer which has spread to multiple parts of the body — are ‘dismal’, scientists say. The five-year survival rate for children with this cancer is very low — some studies suggest less than a quarter reach this milestone. But a small non-randomized retrospective study of a drug called pazopanib has shown that it increases children’s survival without major side-effects. 85% of patients taking the drug survived for two years after diagnosis, and two-thirds reached the end of the second year without their cancer progressing. Researchers urge the development of larger-scale trials to investigate further.

Journal: Frontiers in Oncology

First truly global picture of wide inequalities in care for women’s cancers

London School of Hygiene & Tropical Medicine
Peer-Reviewed Publication

One in five women with breast or cervical cancer in low- and middle-income countries (LMICs) are diagnosed at an early stage, compared with more than one in three in high-income countries (HICs), new research suggests. For ovarian cancer, the proportion of women diagnosed with early-stage disease was generally lower than 20% (one in five) worldwide, although the situation remains slightly worse for women in LMICs.

Journal: The Lancet
Funder: European Research Council

University of Louisville, UofL Health receive $11.5 million to develop new cancer immunotherapies

University of Louisville
Grant and Award Announcement

UofL has received $11.5 million in new funding from the NIH to support continuing research to develop therapies that activate the immune system against cancer and to train the next generation of cancer researchers and oncologists.

Funder: NIH/National Institute of General Medical Sciences

Moffitt study shows gene expression test can help identify melanoma patients at low risk of lymph node spread

H. Lee Moffitt Cancer Center & Research Institute
Peer-Reviewed Publication

A large multicenter clinical trial published in JAMA Surgery shows that a gene expression profile–based test can reliably identify melanoma patients who have a low risk of cancer spreading to their lymph nodes. The findings could help guide decisions about whether to perform sentinel lymph node biopsy, a standard but invasive staging procedure.

Journal: JAMA Surgery
Funder: SkylineDx

ESMO 2025: MSK presents new research, including latest on lung and pancreatic cancer treatments

Memorial Sloan Kettering Cancer Center
Reports and Proceedings

MSK highlights from the recent European Society for Medical Oncology (ESMO) Congress include promising findings on new lung, pancreatic, and colorectal cancer treatments and new insights for how molecular testing can guide personalized medicine.

Meeting: ESMO 25

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