EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 13-Oct-2025 22:11 ET (14-Oct-2025 02:11 GMT/UTC)

One step closer to improving ER+ breast cancer patients’ response to therapy

Baylor College of Medicine
Peer-Reviewed Publication

A new study from researchers at Baylor College of Medicine brings hope for a more personalized approach to treat estrogen receptor-positive (ER+) breast cancer, the most common type of this cancer. The team identified a biomarker in preclinical ER+ breast cancer models that indicates that the tumor is more likely to respond to treatment with CDK4/6 inhibitors. The findings support further clinical studies to determine whether this marker may help identify patients who could benefit from CDK4/6 inhibitors.

Journal: Science Translational Medicine

Many patients with advanced cancer feel their treatment is not aligned with their personal care goals

University of California - Los Angeles Health Sciences
Peer-Reviewed Publication

A new study led by researchers at the UCLA Health Jonsson Comprehensive Cancer Center and the UCLA Palliative Care Research Center, found that many people with advanced cancer report that their treatment does not align with their personal care goals.

Journal: Cancer

Research implicates biomolecular condensates in a type of childhood brain cancer

St. Jude Children's Research Hospital
Peer-Reviewed Publication

Scientists at St. Jude Children’s Research Hospital found that droplets within cells, called condensates, are required for ependymoma formation, creating new opportunities for drug development.

Journal: Nature Cell Biology

Housing aid linked to lower medical financial hardship among U.S. renters with cancer

University of California - Los Angeles Health Sciences
Peer-Reviewed Publication

Government housing assistance was associated with a nearly seven-percentage point lower risk of experiencing financial hardship related to medical expenses among US renters with a history of cancer. The findings demonstrate that this assistance is associated with improvement in overall financial security, quality of life, and health outcomes for renters with cancer.

Journal: JAMA Network Open
Funder: National Institutes of Health/National Center for Advancing Translational Sciences UCLA Clinical and Translational Science Institute

Test detects brain cancers in cerebrospinal fluid with high accuracy

Johns Hopkins Medicine
Peer-Reviewed Publication

A novel, multi-analyte test developed by researchers at the Johns Hopkins Kimmel Cancer Center, its Ludwig Center and the Johns Hopkins Department of Neurosurgery can accurately identify brain cancers using small samples of cerebrospinal fluid (CSF), offering a promising new tool to guide clinical decision-making.

Journal: Cancer Discovery
Funder: National Cancer Institute, Benjamin Baker Endowment, DOD award, Virginia and D.K. Ludwig Fund for Cancer Research., Burroughs Wellcome Career Award for Medical Scientists, Commonwealth Fund, Conrad R. Hilton Foundation, Lustgarten Foundation for Pancreatic Cancer Research

Seroprevalence 36 months after a single-dose bivalent human papillomavirus vaccination among nine to fifteen-year-old girls in Dhaka, Bangladesh

Xia & He Publishing Inc.
Peer-Reviewed Publication

Immunization against human papillomavirus (HPV), particularly with a single-dose vaccine, offers a cost-effective strategy for cervical cancer prevention. This study aimed to evaluate the seroprevalence following a single-dose bivalent HPV vaccine among adolescent girls in Bangladesh and to examine its association with sociodemographic characteristics.

Journal: Cancer Screening and Prevention

Molecular Analysis for Precision Oncology Congress (MAP) 2025: Event Announcement

European Society for Medical Oncology
Meeting Announcement

The congress will be held onsite in Paris, France, from 15-16 September

Association between serum 25-hydroxyvitamin D levels and skin cancer risk

Xia & He Publishing Inc.
Peer-Reviewed Publication

Skin cancer, the most common global malignancy, is linked to ultraviolet (UV)-driven serum 25-hydroxyvitamin D (25(OH)D)synthesis, with its controversial role possibly reflecting cumulative UV exposure. This study aimed to assess the association and causality between 25(OH)D levels and skin cancer risk using the National Health and Nutrition Examination Survey (1999–2018) data and Mendelian randomization (MR) analyses, evaluating 25(OH)D as a screening biomarker.

Journal: Cancer Screening and Prevention

Insights into the role of PAD2-mediated histone citrullination in pancreatic cancer progression

Institute of Science Tokyo
Peer-Reviewed Publication

Peptidyl-arginine deiminase 2 (PAD2) enzyme converts arginine amino acid residues in histone proteins into citrulline groups and promotes tumor cell proliferation in pancreatic ductal adenocarcinoma, report researchers from Institute of Science Tokyo, Japan. Administration of PAD inhibitors reduced PRUNE1 expression and suppressed tumor cell proliferation in both pancreatic cancer cell lines and mouse models. The study thus lays the foundation for future anticancer therapies targeting PAD2 enzymatic activity.

Journal: Molecular Cancer Research
Funder: Japan Agency for Medical Research and Development, Japan Society for the Promotion of Science, Princess Takamatsu Cancer Research Fund

New technique at HonorHealth Research Institute uses ultrasound to activate drugs targeting pancreatic cancer

HonorHealth Research Institute
Reports and Proceedings

HonorHealth Research Institute is combining the power of targeted drugs and ultra-sound technology to shrink the tumors of pancreatic cancer patients whose cancer has not spread to other parts of the body but is too advanced to allow safe surgical removal.

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