EurekAlert! Cancer Research

News Releases

Updates every hour. Last Updated: 13-Dec-2025 18:11 ET (13-Dec-2025 23:11 GMT/UTC)

4-Nov-2025

As millions lag in colon cancer screening, new studies point to strategies to boost uptake and follow-up

Michigan Medicine - University of Michigan
Peer-Reviewed Publication

A pair of new studies examines two aspects of the colon cancer screening process: the preferences of patients and physicians for all currently available colorectal cancer screening options, and the impact of a 2023 federal policy change that eliminated out of pocket costs for those who get an abnormal result on a home-based stool test and then need a colonoscopy.

Journal: Current Medical Research and Opinion
Funder: Exact Sciences Corporation

4-Nov-2025

Wake Forest University School of Medicine scientists uncover cancer treatment strategy that pushes tumor cells past their breaking point

Atrium Health Wake Forest Baptist
Peer-Reviewed Publication

Researchers have uncovered a promising cancer treatment strategy by targeting a mitochondrial protein called peroxiredoxin-3 (PRX3). PRX3 normally acts as a cleanup system inside cancer cells, breaking down hydrogen peroxide before it becomes toxic. The team discovered a compound fragment that binds to PRX3 and switches it off, causing hydrogen peroxide to accumulate beyond the cell’s tolerance. This surge in oxidative stress overwhelms cancer cells, while sparing healthy ones, offering a novel approach to therapy that flips the traditional model of reducing stress into one that exploits cancer’s vulnerability.

Journal: Science Advances
Funder: Wake Forest Innovations Catalyst Fund, Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Center for Redox Biology and Medicine.

4-Nov-2025

NCCN celebrates expanding access to cancer treatment in Africa at 2025 AORTIC Meeting with new NCCN adaptations for Sub-Saharan Africa

National Comprehensive Cancer Network
Business Announcement

As part of the 2025 AORTIC Meeting, the African Cancer Coalition, American Cancer Society, and NCCN showcased the transition from harmonized clinical practice guidelines to the new International Adaptations of NCCN Guidelines for Sub-Saharan Africa, representing how much progress has been made in cancer care access across the region.

4-Nov-2025

RTOG Foundation opens new study testing [177Lu]Lu-DOTA-TATE for adults with meningioma

RTOG Foundation
Business Announcement

RTOG Foundation, a non-profit organization which conducts clinical trials designed to discover more effective cancer therapies, recently opened a new trial RTOG 3523, also known as the “MOMENTUM-1” study, testing the radioactive drug [¹⁷⁷Lu]Lu-DOTA-TATE (hereafter referred to as ¹⁷⁷Lu-Dotatate) in adult who have progressive intracranial grade 1-3 meningioma.

4-Nov-2025

Study confirms sustained reduction in prostate cancer mortality with PSA screening

Tampere University
Peer-Reviewed Publication

A European study has demonstrated a sustained long-term reduction in prostate cancer mortality through prostate-specific antigen (PSA) screening. However, the findings also highlight the issue of overdiagnosis, or the detection of slow-growing cancers that are unlikely to affect a patient’s lifespan, associated with PSA screening. To address this concern, the researchers advocate the development of risk-based screening.

Journal: New England Journal of Medicine

4-Nov-2025

Scanning nanoprobe microscope reveals the hidden flexibility of cancer cells

Nano Life Science Institute (NanoLSI), Kanazawa University
Peer-Reviewed Publication

Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in ACS Applied Nano Materials a new method to precisely measure nuclear elasticity—the stiffness or softness of the cell nucleus—in living cells. By employing a technique called Nanoendoscopy-AFM (NE-AFM), which inserts a nanoneedle probe directly into cells, the team revealed how cancer cell nuclei stiffen or soften depending on chromatin structure and environmental conditions.

The findings provide fundamental insights into how the physical properties of cancer cell nuclei change during disease progression, highlighting their potential as biomarkers for diagnosis and treatment evaluation.

Journal: ACS Applied Nano Materials

4-Nov-2025

New survey reveals men would rather sit in traffic than talk about prostate health

Orlando Health
Reports and Proceedings

A new survey from Orlando Health reveals that over one-third of men (38%) would rather endure stressful situations, such as watching their team lose a big game or being stuck in traffic, than discuss their prostate health. This widespread reluctance to address a common health issue often leads to delayed diagnosis and treatment for conditions like an enlarged prostate.

3-Nov-2025

New nanoparticle therapy shrinks pancreatic tumors and extends survival in preclinical study

University of Miami Miller School of Medicine
Peer-Reviewed Publication

A new study has found for the first time that magnetoelectric nanoparticles — tiny, wirelessly controlled particles activated by magnetic fields — can both locate and destroy pancreatic tumors in preclinical models, offering a potential new approach to minimally invasively treating one of the deadliest cancers.

Journal: Advanced Science

3-Nov-2025

Mass General Brigham researchers harness tumor cells to boost antitumor immunity in preclinical cancer models

Mass General Brigham
Peer-Reviewed Publication

Investigators from Mass General Brigham have developed a way to promote antitumor immunity by hijacking cellular machinery within cancer cells. The study demonstrated that inducing cancer cells to produce an immune-activating molecule led to reduced tumor growth in preclinical models. Results are published in PNAS.

“Tumor cells comprise a significant proportion of the tumor microenvironment but are often under-utilized for immunotherapy,” said corresponding author Natalie Artzi, PhD, a researcher in the Mass General Brigham Department of Medicine. “These findings highlight how tumor cells can be used to actively contribute to their own elimination.”

Journal: Proceedings of the National Academy of Sciences

3-Nov-2025

Extensive LA-area fires altered blood proteins in firefighters, raising health concerns

University of Arizona, Office of Research and Partnerships
Peer-Reviewed Publication

A new study found that firefighters exposed to the Palisades and other fires had changes in their immune system and inflammatory response protein pathways.

Journal: Journal of Occupational and Environmental Medicine