EurekAlert! Cancer Research

News Releases

Updates every hour. Last Updated: 1-May-2025 11:08 ET (1-May-2025 15:08 GMT/UTC)

26-Mar-2025

Revolutionizing protein modification: a new frontier in cancer research

Pohang University of Science & Technology (POSTECH)
Peer-Reviewed Publication

POSTECH Develops Bio-conjugation Technology for Selective Protein Modification in Live Biological Systems.

Journal: Journal of the American Chemical Society

25-Mar-2025

Enzyme engineering opens door to novel therapies for Parkinson’s, cancers and other hard-to-target protein diseases

Scripps Research Institute
Peer-Reviewed Publication

Scientists have long struggled to target proteins that lack defined structure and are involved in cancer, neurodegenerative disorders like Parkinson’s disease, and other serious illnesses. Now, a new study from Scripps Research demonstrates a proof of concept for a new strategy: engineering proteases—enzymes that cut proteins at specific sites—to selectively degrade these elusive targets with high precision in the proteome of human cells.

Journal: Proceedings of the National Academy of Sciences

25-Mar-2025

Glucose revealed as a master regulator of tissue regeneration in Stanford Medicine study

Stanford Medicine
Peer-Reviewed Publication

Glucose is life’s main energy source. But a Stanford Medicine study reveals a surprising role as a master manipulator of tissue maturation, hinting at its importance in diabetes and cancer.

Journal: Cell Stem Cell

25-Mar-2025

Government of Guyana, Mount Sinai Health System and Hess Corporation announce five-year extension of national healthcare initiative.

The Mount Sinai Hospital / Mount Sinai School of Medicine
Business Announcement

Initiative aims to transform Guyana’s public health system by 2030 with world-class healthcare services accessible to all citizens, especially vulnerable communities

25-Mar-2025

Milk as Medicine: New Study Shows Breast Milk Transforms Challenges into Triumphs

University of Oklahoma
Peer-Reviewed Publication

In 2010, University of Oklahoma researcher David Fields, Ph.D., was pouring over research data when he discovered something he thought was odd: His data showed that at 6 months of age, formula-fed babies born of mothers who were categorized as medically obese weighed about 5% units less fat than breastfed babies in the same dataset. That discovery struck him as unusual and led him on a research journey to better understand breast milk. Now, he’s studying the connections between maternal gestational diabetes, breastfeeding and infant health.

Journal: Journal of the American Medical Association

25-Mar-2025

CU Cancer Center researchers identify the ‘switch’ that allows intestinal cells to regenerate after injury

University of Colorado Anschutz Medical Campus
Peer-Reviewed Publication

Researchers from the University of Colorado Cancer Center have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer.

Peter Dempsey, PhD, professor of pediatrics–developmental biology in the CU School of Medicine, and Justin Brumbaugh, PhD, assistant professor of molecular, cellular, and developmental biology at CU Boulder, recently published a paper in the journal Nature Cell Biology showing the importance of the H3K36 methylation process in regulating plasticity and regeneration in intestinal cells.

Journal: Nature Cell Biology

25-Mar-2025

Engineering antibodies with a novel fusion protein

Sanford Burnham Prebys
Peer-Reviewed Publication

Even with significant expansion in the global market for antibodies used in clinical care and research, scientists recognize that there is still untapped potential for finding new antibodies. Many proteins group together in what are called protein complexes to carry out biological functions. The traditional method of generating antibodies by immunizing animals struggles to make antibodies related to these protein complexes.

Scientists at Sanford Burnham Prebys and Eli Lilly and Company published findings March 5, 2025, in the Journal of Immunology demonstrating that fusing protein complexes together adds stability during immunization and enables antibody generation.

Journal: Journal of Immunology

25-Mar-2025

Lupus-related antibody shows promise in enhancing cancer treatment efficacy

Yale University
Peer-Reviewed Publication

New Haven, Conn. — Yale scientists have discovered a promising way to trigger immune responses against certain tumors, using a lupus-related antibody that can slip, undetected, into “cold” tumors and flip on an immune response that has been turned off by cancer. The research, published in Science Signaling on March 25, offers new findings that could help improve therapies for glioblastoma and other aggressive cancers that are difficult to treat.

Journal: Science Signaling

25-Mar-2025

Study unravels mystery of cancer-fueling enzyme—could lead to new therapies

University of Colorado at Boulder
Peer-Reviewed Publication

New research offers unprecedented insight into how an enigmatic enzyme, known as CDK7, drives the cell cycle and cell proliferation.

Journal: Science Advances

25-Mar-2025

Disparities in use of MRI to detect prostate cancer

Thomas Jefferson University
Peer-Reviewed Publication

A patient’s race and location may influence diagnostic testing for prostate tumors.